Evidence map›Paper›PMID 29036606›Full record

ArticleAmerican journal of epidemiology2018

Socioeconomic Status and Childhood Cancer Incidence: A Population-Based Multilevel Analysis.

Rebecca D Kehm, Logan G Spector, Jenny N Poynter, David M Vock, Theresa L Osypuk

Open access · bronzeAbstract read
In one paragraph

Article in American journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Identifying caregiver-reported modifiable barriers to pediatric oncology clinical trial enrollment and participation.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  7. Article
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  10. Examining the association between socioeconomic status, clinical assessment, and dental caries experience in oncology patients: a 5-year review of a tertiary-care hospital.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
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  19. Insights into the mechanisms of angiogenesis in hepatoblastoma.Frontiers in cell and developmental biology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rebecca D KehmUniversity of Minnesota School of Public Health, Division of Epidemiology and Community Health, Minneapolis, Minnesota.
Logan G SpectorUniversity of Minnesota, Division of Epidemiology and Clinical Research, Department of Pediatrics, Minneapolis, Minnesota.
Jenny N PoynterUniversity of Minnesota, Division of Epidemiology and Clinical Research, Department of Pediatrics, Minneapolis, Minnesota.
David M VockUniversity of Minnesota School of Public Health, Division of Biostatistics, Minneapolis, Minnesota.
Theresa L OsypukUniversity of Minnesota School of Public Health, Division of Epidemiology and Community Health, Minneapolis, Minnesota.
University of Minnesota · USMinnesota Department of Health · US

Funding

Translational Pediatric Cancer Epidemiology Research Training GrantT32CA099936 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Logan G. Spector · 2004 to 2026
$5.1M
Minnesota Population Center Science and Technical CoreP2CHD041023 · NICHD · UNIVERSITY OF MINNESOTA · PI THERESA LOUISE OSYPUK · 2016 to 2026
$4.3M
CANCER EPIDEMIOLOGY/BIOSTATISTICS/ENVIRONMENTAL SCIENCEST32CA009529 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI NEUGUT, ALFRED I. · 1985 to 2012
$4.3M
Training Program in Cancer-related Population SciencesT32CA094061 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NEUGUT, ALFRED I., TERRY, MARY BETH · 2017 to 2021
$1.1M
NCI NIH HHS T32 CA009529NCI NIH HHS T32 CA094061NCI NIH HHS T32 CA099936NICHD NIH HHS P2C HD041023
6 · The paper itself

Abstract

The etiology of childhood cancers remains largely unknown, especially regarding environmental and behavioral risk factors. Unpacking the association between socioeconomic status (SES) and incidence may offer insight into such etiology. We tested associations between SES and childhood cancer incidence in a population-based case-cohort study (source cohort: Minnesota birth registry, 1989-2014). Cases, ages 0-14 years, were linked from the Minnesota Cancer Surveillance System to birth records through probabilistic record linkage. Controls were 4:1 frequency matched on birth year (2,947 cases and 11,907 controls). We tested associations of individual-level (maternal education) and neighborhood-level (census tract composite index) SES using logistic mixed models. In crude models, maternal education was positively associated with incidence of acute lymphoblastic leukemia (odds ratio (OR) = 1.10, 95% confidence interval (CI): 1.02, 1.19), central nervous system tumors (OR = 1.12, 95% CI: 1.04, 1.21), and neuroblastoma (OR = 1.15, 95% CI: 1.02, 1.30). Adjustment for established risk factors-including race/ethnicity, maternal age, and birth weight-substantially attenuated these positive associations. Similar patterns were observed for neighborhood-level SES. Conversely, higher maternal education was inversely associated with hepatoblastoma incidence (adjusted OR = 0.70, 95% CI: 0.51, 0.98). Overall, beyond the social patterning of established demographic and pregnancy-related exposures, SES is not strongly associated with childhood cancer incidence.

Indexed as

AdolescentAdultCase-Control StudiesChildChild, PreschoolFemaleHumansIncidenceInfantMinnesotaNeoplasmsPregnancyPrenatal Exposure Delayed EffectsSocial ClassYoung Adult

Identifiers

PMID29036606
PMCPMC5928452
OpenAlexW2757400234

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.