Evidence map›Paper›PMID 29036522›Full record

ReviewAlcohol and alcoholism (Oxford, Oxfordshire)2017

More Alcohol, More Liver Injury: Not Always True.

Irina Kirpich, Craig McClain

Open access · hybridAbstract readReview
In one paragraph

Review in Alcohol and alcoholism (Oxford, Oxfordshire), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Irina KirpichDepartment of Medicine, University of Louisville School of Medicine, 505S Hancock Street, CTR511, Louisville, KY 40202-1617, USA.
Craig McClainDepartments of Medicine, Pharmacology & Toxicology, 505S Hancock Street, CTR503, Louisville, KY 40202-1617, USA.
University of Louisville · US

Funding

The role of dietary unsaturated fat and inflammasome in alcoholic liver diseaseR01AA024102 · NIAAA · UNIVERSITY OF LOUISVILLE · PI KIRPICH, IRINA A. · 2016 to 2020
$1.7M
NIAAA NIH HHS R01 AA024102
6 · The paper itself

Abstract

An animal model of alcoholic liver disease (ALD) that recapitulates human disease is an unmet need. An alcohol-preferring strain and WT mice were fed alcohol by different techniques and with different diet compositions. Interestingly, the greatest alcohol consumers did not develop the worst ALD. This editorial highlights how diet and the gut microbiome/metabolome may influence the development/severity of ALD.

Indexed as

Disease Models, AnimalAlcohol DrinkingAnimalsGastrointestinal MicrobiomeHumansLiver Diseases, AlcoholicMiceRisk Factors

Identifiers

PMID29036522
PMCPMC6355099
OpenAlexW2760656460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.