ArticleNucleic acids research2017
Global inhibition of transcription causes an increase in histone H2A.Z incorporation within gene bodies.
Article in Nucleic acids research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Article
- Mechanisms of gene regulation by SRCAP and H2A.Z.Nature communications · 2026Article
- Skin Epidermal Progenitor Maintenance by the SRCAP-H2A.Z Axis Downstream to Extracellular Signal-Regulated Kinase and mTOR Signaling.The Journal of investigative dermatology · 2026Article
- IMPACTS OF DNA METHYLATION ON H2A.Z DEPOSITION AND NUCLEOSOME STABILITY.bioRxiv : the preprint server for biology · 2025Article
- H2A.Z is essential for oocyte maturation and fertility in female mouse.Nature structural & molecular biology · 2025Article
- HSV-1 infection induces a downstream shift of the +1 nucleosome.Journal of virology · 2025Article
- RNA polymerase II coordinates histone deacetylation at active promoters.Science advances · 2025Article
- RNA Polymerase II coordinates histone deacetylation at active promoters.bioRxiv : the preprint server for biology · 2024Article
- Structural and Biochemical Characterization of the Nucleosome Containing Variants H3.3 and H2A.Z.Epigenomes · 2024Article
- Structural insights into histone exchange by human SRCAP complex.Cell discovery · 2024Article
- Histone variant H2A.Z modulates nucleosome dynamics to promote DNA accessibility.Nature communications · 2023Article
- Histone variants and chromatin structure, update of advances.Computational and structural biotechnology journal · 2023Review
- The Role of the Histone Variant H2A.Z in Metazoan Development.Journal of developmental biology · 2022Review
- Structural basis of chromatin regulation by histone variant H2A.Z.Nucleic acids research · 2021Article
- The histone chaperone Anp32e regulates memory formation, transcription, and dendritic morphology by regulating steady-state H2A.Z binding in neurons.Cell reports · 2021Article
- MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism-like behaviors.EMBO reports · 2021Article
- A dual role for H2A.Z.1 in modulating the dynamics of RNA polymerase II initiation and elongation.Nature structural & molecular biology · 2021Article
- Review
- De novo activated transcription of inserted foreign coding sequences is inheritable in the plant genome.PloS one · 2021Article
- Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication.Cell reports · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
H2A.Z histone variant is an important regulator of gene transcription, which is enriched at regulatory regions but is also found within gene bodies. Recent evidence suggests that active recruitment of H2A.Z within gene bodies is required to induce gene repression. In contrast to this view, we show that global inhibition of transcription results in H2A.Z accumulation at gene transcription start sites, as well as within gene bodies. Our results indicate that accumulation of H2A.Z within repressed genes can also be a consequence of the repression of gene transcription rather than an active mechanism required to establish the repression.
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