Evidence map›Paper›PMID 29036391›Full record

ArticleSchizophrenia bulletin2018

Improvement in Negative Symptoms and Functioning in Cognitive-Behavioral Social Skills Training for Schizophrenia: Mediation by Defeatist Performance Attitudes and Asocial Beliefs.

Eric Granholm, Jason Holden, Matthew Worley

Registry-linked trialAbstract read
In one paragraph

Article in Schizophrenia bulletin, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06127004 (Metacognitive Training for Negative Symptoms), which is not on this map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06127004 narecruitingnot on this mapstarted 2024, after this paper: background citation

Metacognitive Training for Negative Symptoms (MCT Minus)

TypeinterventionalSponsorSormland County Council, SwedenRan2024 to 2032Enrolled90ConditionsNegative Symptoms in SchizophreniaArmsMetacognitive Training for Negative Symptoms (MCT), Supportive Counselling
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Cognitive behavioural therapy (group) for schizophrenia.The Cochrane database of systematic reviews · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Eric GranholmDepartment of Psychiatry, University of California, San Diego, La Jolla, CA.
Jason HoldenDepartment of Psychiatry, University of California, San Diego, La Jolla, CA.
Matthew WorleyDepartment of Psychiatry, University of California, San Diego, La Jolla, CA.

Funding

Cognitive Behavioral Skills Training for SchizophreniaR01MH071410 · NIMH · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI GRANHOLM, ERIC L · 2005 to 2009
$2.9M
Behavioral economic mechanisms of prescription opioid addiction in chronic painK23DA039348 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WORLEY, MATTHEW J. · 2016 to 2020
$1.0M
NIDA NIH HHS K23 DA039348NIMH NIH HHS R01 MH071410
6 · The paper itself

Abstract

Psychosocial interventions have significant but modest impact on negative symptoms and functioning in schizophrenia. Identifying mechanisms of change in these interventions can inform treatment targets to strengthen these interventions. A number of studies have found associations between dysfunctional attitudes negative symptoms and functioning in schizophrenia. We previously found improvement in experiential negative symptoms and functioning in cognitive-behavioral social skills training (CBSST) in participants with schizophrenia (N = 149), and the present study examined whether improvements in CBSST in that trial were mediated by the group effect on defeatist performance attitudes and asocial beliefs. In multilevel mediation analyses, the effect of treatment group on experiential negative symptoms and functioning was mediated prospectively through defeatist attitudes but asocial beliefs only mediated effects on experiential negative symptoms. The findings suggest that cognitive-behavioral therapy interventions that target dysfunctional attitudes can lead to improvement in negative symptoms and functioning in schizophrenia.

Indexed as

AttitudeOutcome Assessment, Health CarePsychotic DisordersSchizophreniaSchizophrenic PsychologySocial SkillsAdultCognitive Behavioral TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedMotivationRandomized Controlled Trials as Topic

Identifiers

PMID29036391
PMCPMC5890456

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.