Evidence map›Paper›PMID 29036228›Full record

ArticlePloS one2017

Factors associated to acceptable treatment adherence among children with chronic kidney disease in Guatemala.

Brooke M Ramay, Alejandro Cerón, Luis Pablo Méndez-Alburez, Randall Lou-Meda

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Little kidneys amid large global inequities.Pediatric nephrology (Berlin, Germany) · 2026
    Review
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  10. Factors associated with chronic kidney disease of non-traditional causes among children in Guatemala.Revista panamericana de salud publica = Pan American journal of public health · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brooke M RamayDepartment of Pharmaceutical Chemistry, Universidad del Valle de Guatemala, Guatemala City, Guatemala.ORCID http://orcid.org/0000-0001-8527-4067
Alejandro CerónDepartment of Anthropology, University of Denver, Denver, Colorado, United States of America.
Luis Pablo Méndez-AlburezFundación para el Niño Enfermo Renal-FUNDANIER, Hospital Roosevelt, Guatemala City, Guatemala.
Randall Lou-MedaFundación para el Niño Enfermo Renal-FUNDANIER, Hospital Roosevelt, Guatemala City, Guatemala.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric patients with Chronic Kidney Disease face several barriers to medication adherence that, if addressed, may improve clinical care outcomes. A cross sectional questionnaire was administered in the Foundation for Children with Kidney Disease (FUNDANIER, Guatemala City) from September of 2015 to April of 2016 to identify the predisposing factors, enabling factors and need factors related to medication adherence. Sample size was calculated using simple random sampling with a confidence level of 95%, confidence interval of 0.05 and a proportion of 87%. A total of 103 participants responded to the questionnaire (calculated sample size was 96). Independent variables were defined and described, and the bivariate relationship to dependent variables was determined using Odds Ratio. Multivariate analysis was carried out using logistic regression. The mean adherence of study population was 78% (SD 0.08, max = 96%, min = 55%). The mean adherence in transplant patients was 82% (SD 7.8, max 96%, min 63%), and the mean adherence in dialysis patients was 76% (SD 7.8 max 90%, min 55%). Adherence was positively associated to the mother's educational level and to higher monthly household income. Together predisposing, enabling and need factors illustrate the complexities surrounding adherence in this pediatric CKD population. Public policy strategies aimed at improving access to comprehensive treatment regimens may facilitate treatment access, alleviating economic strain on caregivers and may improve adherence outcomes.

Indexed as

Drug MonitoringAdolescentChildFemaleGuatemalaHealth PolicyHumansMaleMultivariate AnalysisRenal Insufficiency, ChronicSurveys and Questionnaires

Identifiers

PMID29036228
PMCPMC5643062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.