Evidence map›Paper›PMID 29036012›Full record

ReviewMedical care2017

A Fresh Perspective on a Familiar Problem: Examining Disparities in Knee Osteoarthritis Using a Markov Model.

Taruja D Karmarkar, Anne Maurer, Michael L Parks, Thomas Mason, Ana Bejinez-Eastman, Melvyn Harrington, Randall Morgan, Mary I O'Connor, James E Wood, Darrell J Gaskin

Open access · greenAbstract readReview
In one paragraph

Review in Medical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  12. Association between knee symptoms, change in knee symptoms over 6-9 years, and SF-6D health state utility among middle-aged Australians.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Article
  13. Article
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  16. Appropriate Use Criteria for the Nonarthroplasty Treatment of Knee Osteoarthritis in Veterans.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2019
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 1 country.

Taruja D Karmarkar*Department of Health Policy & Management†Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD‡Zimmer Biomet Inc., Warsaw, IN§Hospital for Special Surgery, New York, NY∥US Department of Health and Human Services, Office of the National Coordinator, Washington, DC¶PIH Health, Whittier, CA#Baylor College of Medicine, Houston, TX**W. Montague Cobb/NMA Health Institute, Washington, DC††Center for Musculoskeletal Care at Yale School of Medicine and Yale-New Haven Hospital, New Haven, CT‡‡MedStar Harbor Hospital, Baltimore, MD.
Anne Maurer
Michael L Parks
Thomas Mason
Ana Bejinez-Eastman
Melvyn Harrington
Randall Morgan
Mary I O'Connor
James E Wood
Darrell J Gaskin
Johns Hopkins University · USBaylor College of Medicine · USHospital for Special Surgery · USMedStar Harbor Hospital · USOffice of the National Coordinator for Health Information Technology · USPIH Health · USYale New Haven Hospital · USZimmer Biomet (United States) · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

backgroundDisparities in the presentation of knee osteoarthritis (OA) and in the utilization of treatment across sex, racial, and ethnic groups in the United States are well documented.

objectivesWe used a Markov model to calculate lifetime costs of knee OA treatment. We then used the model results to compute costs of disparities in treatment by race, ethnicity, sex, and socioeconomic status. RESEARCH

designWe used the literature to construct a Markov Model of knee OA and publicly available data to create the model parameters and patient populations of interest. An expert panel of physicians, who treated a large number of patients with knee OA, constructed treatment pathways. Direct costs were based on the literature and indirect costs were derived from the Medical Expenditure Panel Survey.

resultsWe found that failing to obtain effective treatment increased costs and limited benefits for all groups. Delaying treatment imposed a greater cost across all groups and decreased benefits. Lost income because of lower labor market productivity comprised a substantial proportion of the lifetime costs of knee OA. Population simulations demonstrated that as the diversity of the US population increases, the societal costs of racial and ethnic disparities in treatment utilization for knee OA will increase.

conclusionsOur results show that disparities in treatment of knee OA are costly. All stakeholders involved in treatment decisions for knee OA patients should consider costs associated with delaying and forgoing treatment, especially for disadvantaged populations. Such decisions may lead to higher costs and worse health outcomes.

Indexed as

Models, EconomicArthroplasty, Replacement, KneeCost-Benefit AnalysisFemaleHealth Care CostsHealthcare DisparitiesHealth Services Needs and DemandHealth Status DisparitiesHumansMaleOsteoarthritis, KneeUnited States

Identifiers

PMID29036012
PMCPMC5690313
OpenAlexW2762309545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.