Evidence map›Paper›PMID 29035516›Full record

ArticleChemical research in toxicology2017

Potential Metabolic Activation of Representative Alkylated Polycyclic Aromatic Hydrocarbons 1-Methylphenanthrene and 9-Ethylphenanthrene Associated with the Deepwater Horizon Oil Spill in Human Hepatoma (HepG2) Cells.

Meng Huang, Clementina Mesaros, Linda C Hackfeld, Richard P Hodge, Ian A Blair, Trevor M Penning

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Aryl hydrocarbon receptor-dependent toxicity by retene requires metabolic competence.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Article
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  8. Using Precision Environmental Health Principles in Risk Evaluation and Communication of the Deepwater Horizon Oil Spill.New solutions : a journal of environmental and occupational health policy : NS · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Meng Huang
Clementina Mesaros
Linda C HackfeldSynthetic Organic Chemistry Core, Center in Environmental Toxicology, University of Texas Medical Branch at Galveston , Galveston, Texas 77555-1110, United States.
Richard P HodgeSynthetic Organic Chemistry Core, Center in Environmental Toxicology, University of Texas Medical Branch at Galveston , Galveston, Texas 77555-1110, United States.
Ian A Blair
The University of Texas Medical Branch at Galveston · US

Funding

Translational Research Support CoreP30ES013508 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI Rebecca A Simmons · 2006 to 2026
$35.3M
Synthetic Organic Chemistry CoreP30ES006676 · NIEHS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ELFERINK, CORNELIS JOHAN · 1995 to 2017
$21.7M
Project 3: Toxicology of Petrogenic PAH in the Gulf Oil SpillU19ES020676 · NIEHS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ELFERINK, CORNELIS JOHAN · 2011 to 2015
$7.9M
NIEHS NIH HHS P30 ES006676NIEHS NIH HHS P30 ES013508NIEHS NIH HHS U19 ES020676
6 · The paper itself

Abstract

Exposure to petrogenic polycyclic aromatic hydrocarbons (PPAHs) is the major human health hazard associated with the Deepwater Horizon oil spill. Alkylated phenanthrenes are the most abundant PPAHs present in the crude oil and could contaminate the food chain. We describe the metabolism of a C

Indexed as

Petroleum PollutionAlkylationCarcinoma, HepatocellularChromatography, High Pressure LiquidHep G2 CellsHumansMolecular StructurePetroleumPhenanthrenesSpectrophotometry, Ultraviolet1-methylphenanthrene9-ethylphenanthrenePetroleumPhenanthrenes

Identifiers

PMID29035516
PMCPMC5734992
OpenAlexW2765582613

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.