ReviewKorean circulation journal2017
Where Is the "Optimal" Fontan Hemodynamics?
Review in Korean circulation journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed.
- Liver stiffness measured by transient elastography is not predictive of mortality or adverse events in adult patients with Fontan associated liver disease.International journal of cardiology. Congenital heart disease · 2026Article
- Influence of Heart Rate on Hemodynamics in Fontan Circulation.Pediatric cardiology · 2026Article
- Fenestration Re-creation for Early Fontan Deterioration: Long-Term Hemodynamic and Clinical Outcomes.Pediatric cardiology · 2026Article
- The Canadian Fontan Connection (CANFON): Protocol for a National Lifespan Cohort of People Living With a Fontan Circulation.CJC pediatric and congenital heart disease · 2026Article
- Sustained remission of post-Fontan protein-losing enteropathy achieved by combination therapy with high-dose spironolactone and the somatostatin analogue octreotide: a case report.BMC pediatrics · 2026Article
- Association of Pre-Fontan Hemodynamics With Long-Term Outcomes After Fontan Palliation: A Study From the Pediatric Cardiac Care Consortium.Circulation · 2026Article
- Exercise hemodynamics in adults with Fontan circulation assessed by noninvasive impedance cardiography.Frontiers in cardiovascular medicine · 2026Article
- Plasma Lipidomic Alterations in Fontan Circulation Reflect Cardiovascular Functional Reserve.Metabolites · 2025Article
- Role of strain imaging for risk stratification in Fontan patients with normal ventricular ejection fraction.European heart journal. Cardiovascular Imaging · 2025Article
- Oversized Conduits Predict Stenosis in Tissue Engineered Vascular Grafts.JACC. Basic to translational science · 2025Article
- Fontan haemodynamics in adults with obesity compared with overweight and normal body mass index: a retrospective invasive exercise study.European journal of preventive cardiology · 2025Article
- Blood Biomarkers as a Non-Invasive Method for the Assessment of the State of the Fontan Circulation.Journal of clinical medicine · 2025Review
- Investigation of a chronic single-stage sheep Fontan model.JTCVS open · 2024Article
- Robotic-assisted Lymphovenous Anastomosis of the Central Lymphatic System.Plastic and reconstructive surgery. Global open · 2024Article
- Association of patient-level characteristics with long-term outcomes after Fontan palliation: Rationale, design, and baseline characteristics of the Pediatric Cardiac Care Consortium Fontan cohort study.American heart journal · 2024Article
- Article
- Exercise catheterization in adults post-Fontan with normal and abnormal haemodynamic criteria: Insights into normal Fontan physiology.European journal of heart failure · 2024Article
- Ideal chest compression site for cardiopulmonary resuscitation in fontan circulation patients with dextrocardia.BMC cardiovascular disorders · 2024Article
- Switching the Left and the Right Hearts: A Novel Bi-ventricle Mechanical Support Strategy with Spared Native Single-Ventricle.Annals of biomedical engineering · 2023Article
- Predictors of protein losing enteropathy after Fontan completion: An 8-year retrospective study at Sheikh Khalifa Medical City.Global cardiology science & practice · 2023Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fontan circulation is generally characterized by high central venous pressure, low cardiac output, and slightly low arterial oxygen saturation, and it is quite different from normal biventricular physiology. Therefore, when a patient with congenital heart disease is selected as a candidate for this type of circulation, the ultimate goals of therapy consist of 2 components. One is a smooth adjustment to the new circulation, and the other is long-term circulatory stabilization after adjustment. When either of these goals is not achieved, the patient is categorized as having "failed" Fontan circulation, and the prognosis is dismal. For the first goal of smooth adjustment, a lot of effort has been made to establish criteria for patient selection and intensive management immediately after the Fontan operation. For the second goal of long-term circulatory stabilization, there is limited evidence of successful strategies for long-term hemodynamic stabilization. Furthermore, there have been no data on optimal hemodynamics in Fontan circulation that could be used as a reference for patient management. Although small clinical trials and case reports are available, the results cannot be generalized to the majority of Fontan survivors. We recently reported the clinical and hemodynamic characteristics of early and late failing Fontan survivors and their association with all-cause mortality. This knowledge could provide insight into the complex Fontan pathophysiology and might help establish a management strategy for long-term hemodynamic stabilization.
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