ArticleThe Permanente journal2018
Lifestyle Medicine: A Brief Review of Its Dramatic Impact on Health and Survival.
Article in The Permanente journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
103 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Citrulline supplementation in postmenopausal women: a systematic review of vascular, muscular, and metabolic effects.BMC women's health · 2026Pooled it
- The association between physical activity and risk of gastric cancer; an umbrella review.BMC gastroenterology · 2024Pooled it
- A mixed methods systematic review of multimodal non-pharmacological interventions to improve cognition for people with dementia.Dementia (London, England) · 2020Pooled it
- The feasibility of a dietary and lifestyle behaviour change intervention among low-income Latinas and Indigenous Mexicans in rural desert communities: a pilot randomised controlled trial.Public health nutrition · 2026Trial
- Prehabilitative versus rehabilitative exercise in prostate cancer patients undergoing prostatectomy.Journal of cancer research and clinical oncology · 2023Trial
- Intervention effects on self-control decrease speed of biological aging mediated by changes in substance use: A longitudinal study of African American youth.Family process · 2022Trial
- Relapse Prevention by Plant-Based Diet Incorporated into Induction Therapy for Ulcerative Colitis: A Single-Group Trial.The Permanente journal · 2019Trial
- "It's Just a Matter of Doing It": Women Veterans' Experiences with Changing Behavior for Cardiovascular Risk Reduction.Journal of general internal medicine · 2026Article
- Article
- Test-retest reliability and internal consistency of the Occupational Resilience Measure (ORM 1.0).The human occupation & wellbeing journal · 2026Article
- Biochemical Mechanisms of Cellular Stress Adaptation in the Pathogenesis of Chronic Diseases.Molecules (Basel, Switzerland) · 2026Review
- Employed cancer survivors develop a peer-support intervention to improve social connections: a participatory design study.Frontiers in aging · 2026Article
- Building on the Doha Declaration: a white paper on advancing lifestyle medicine for non-communicable disease prevention and health system transformation.Frontiers in public health · 2026Article
- Gut microbiome, stress and interventional strategies using hardy animals.Future science OA · 2025Review
- The Role of Nutrition in Low Back Pain: A Narrative Review and Clinical Implications.American journal of lifestyle medicine · 2025Review
- Lifestyle Medicine Education in Health Professionals Curricula: A Systematic Review and Meta-Analysis.American journal of lifestyle medicine · 2025Review
- Capsaicinoid Glucoside Attenuates Lipid Accumulation in HepG2 Cells Through TRPV1/AMPK-Dependent Signaling Pathway.Food science & nutrition · 2025Article
- Lifestyle Medicine Pillars and Pedagogies in Pre-registration Health Profession Degrees: A Scoping Review.Medical science educator · 2025Review
- Lifestyle Knowledge and Behavior Among Stroke and High-Risk Younger Adult Patients Through Sex, Age and Stroke Status Differences: A Cross-Sectional Study.American journal of lifestyle medicine · 2025Article
- Patient Expectations: A Qualitative Study on What Patients Want From Their Healthcare Providers to Support Them in Healthy Aging.American journal of lifestyle medicine · 2025Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By ignoring the root causes of disease and neglecting to prioritize lifestyle measures for prevention, the medical community is placing people at harm. Advanced nations, influenced by a Western lifestyle, are in the midst of a health crisis, resulting largely from poor lifestyle choices. Epidemiologic, ecologic, and interventional studies have repeatedly indicated that most chronic illnesses, including cardiovascular disease, cancer, and type 2 diabetes, are the result of lifestyles fueled by poor nutrition and physical inactivity.In this article, we describe the practice of lifestyle medicine and its powerful effect on these modern instigators of premature disability and death. We address the economic benefits of prevention-based lifestyle medicine and its effect on our health care system: A system on the verge of bankruptcy. We recommend vital changes to a disastrous course. Many deaths and many causes of pain, suffering, and disability could be circumvented if the medical community could effectively implement and share the power of healthy lifestyle choices. We believe that lifestyle medicine should become the primary approach to the management of chronic conditions and, more importantly, their prevention. For future generations, for our own health, and for the Hippocratic Oath we swore to uphold ("First do no harm"), the medical community must take action. It is our hope that the information presented will inspire our colleagues to pursue lifestyle medicine research and incorporate such practices into their daily care of patients. The time to make this change is now.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.