Evidence map›Paper›PMID 29034677›Full record

ArticleAnalytical chemistry2017

Rapid Enrichment and Sensitive Detection of Multiple Metal Ions Enabled by Macroporous Graphene Foam.

Xiaoni Fang, Yang Liu, Luis Jimenez, Yaokai Duan, Gary Brent Adkins, Liang Qiao, Baohong Liu, Wenwan Zhong

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Xiaoni FangDepartment of Chemistry, University of California , Riverside, 92521 California, United States.
Yang LiuDepartment of Chemistry, University of California , Riverside, 92521 California, United States.
Luis JimenezDepartment of Chemistry, University of California , Riverside, 92521 California, United States.
Yaokai DuanDepartment of Chemistry, University of California , Riverside, 92521 California, United States.
Gary Brent AdkinsDepartment of Chemistry, University of California , Riverside, 92521 California, United States.
Liang QiaoDepartment of Chemistry, Institute of Biomedical Sciences and State Key Lab of Molecular Engineering of Polymers, Shanghai Stomatological Hospital, Fudan University , Shanghai 200433, China.ORCID 0000-0002-6233-8459
Baohong LiuDepartment of Chemistry, Institute of Biomedical Sciences and State Key Lab of Molecular Engineering of Polymers, Shanghai Stomatological Hospital, Fudan University , Shanghai 200433, China.ORCID 0000-0002-0660-8610
Wenwan ZhongDepartment of Chemistry, University of California , Riverside, 92521 California, United States.ORCID 0000-0002-3317-3464
University of California, Riverside · USFudan University · CN

Funding

3-Dimensional profile of circulating miRNA for early cancer detectionR01CA188991 · NCI · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI ZHONG, WENWAN · 2015 to 2018
$1.3M
NCI NIH HHS R01 CA188991
6 · The paper itself

Abstract

Nanomaterials have shown great promise in advancing biomedical and environmental analysis because of the unique properties originated from their ultrafine dimensions. In general, nanomaterials are separately applied to either enhance detection by producing strong signals upon target recognition or to specifically extract analytes taking advantage of their high specific surface area. Herein, we report a dual-functional nanomaterial-based platform that can simultaneously enrich and enable sensitive detection of multiple metal ions. The macroporous graphene foam (GF) we prepared displays abundant phosphate groups on the surface and can extract divalent metal ions via metal-phosphate coordination. The enriched metal ions then activate the metal-responsive DNAzymes and produce the fluorescently labeled single-stranded DNAs that are adsorbed and quenched by the GF. The resultant fluorescence reduction can be used for metal quantitation. The present work demonstrated duplexed detection of Pb

Indexed as

Limit of DetectionAdsorptionBiosensing TechniquesCopperDNA, CatalyticFluorescent DyesGraphiteHumansLeadPorosityTime FactorsWaterCopperDNA, CatalyticFluorescent DyesGraphiteLeadWater

Identifiers

PMID29034677
PMCPMC5687914
OpenAlexW2765212497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.