Evidence map›Paper›PMID 29034437›Full record

ArticleInternational journal of colorectal disease2017

Management of early anal cancer: need for guidelines and standardisation.

Michael P Jones, Susan Carroll, Jarad Martin, Richard Hillman, Andrew Grulich, Dianne O'Connell, Christopher Young, Isobel Mary Poynten

Abstract read
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In one paragraph

Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 2 countries.

Michael P JonesDepartment of Radiation Oncology, Princess Margaret Cancer Centre, Toronto, ON, Canada. mpjones85@gmail.com.
Susan CarrollDepartment of Radiation Oncology, Chris O'Brien Lifehouse, Camperdown, NSW, Australia.
Jarad MartinSchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.
Richard HillmanSt Vincent's Hospital, Darlinghurst, NSW, Australia.
Andrew GrulichKirby Institute, University of New South Wales, Kensington, NSW, Australia.
Dianne O'ConnellSchool of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.
Christopher YoungRoyal Prince Alfred Hospital, Camperdown, NSW, Australia.
Isobel Mary PoyntenKirby Institute, University of New South Wales, Kensington, NSW, Australia.
UNSW Sydney · AUCalvary Mater Newcastle Hospital · AUCancer Council NSW · AUChris O’Brien Lifehouse · AUPrincess Margaret Cancer Centre · CASt Vincent's Hospital Sydney · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe optimal management of early squamous cell carcinoma of the anal canal (AC) is yet to be determined. This study investigated current practice in the management of early AC.

methodsA patterns of care survey was completed by Australian surgeons and radiation oncologists. Specific topics addressed were as follows: geographical location of practice, staging of disease, treatment approaches to T1N0 tumours and grade 3 anal intra-epithelial neoplasia (AIN3) lesions, radiotherapy planning, toxicities, follow-up and clinical trial involvement.

resultsSixty-four responses were obtained. For the management of T1N0 disease, half the respondents recommended standard dose chemo-radiotherapy (CRT) and one third recommended wide local excision (WLE). For the management of AIN3, half recommended WLE while a quarter advocated observation.

conclusionsThis study reveals a significant variation in the management of early AC. The development of guidelines specific to the treatment of early AC could standardise treatment while further research is required to define the optimal management of T1N0 AC and AIN.

Indexed as

Anus NeoplasmsAustraliaCarcinoma in SituCarcinoma, Squamous CellClinical Trials as TopicGuideline AdherenceHealthcare DisparitiesHealth Care SurveysHumansNeoplasm StagingPractice Guidelines as TopicPractice Patterns, Physicians'Radiation OncologistsSurgeonsTreatment OutcomeAnal cancerAnal intra-epithelial neoplasiaChemo-radiotherapy

Identifiers

PMID29034437
OpenAlexW2763472964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.