Evidence map›Paper›PMID 29034219›Full record

ReviewFrontiers in cellular and infection microbiology2017

Rab GTPases in Immunity and Inflammation.

Akriti Prashar, Laura Schnettger, Elliott M Bernard, Maximiliano G Gutierrez

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 125 citations in OpenAlex.

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  17. Cytokines reprogram airway sensory neurons in asthma.bioRxiv : the preprint server for biology · 2024
    Article
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16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Akriti PrasharHost-Pathogen Interactions in Tuberculosis Laboratory, Francis Crick Institute, London, United Kingdom.
Laura SchnettgerHost-Pathogen Interactions in Tuberculosis Laboratory, Francis Crick Institute, London, United Kingdom.
Elliott M BernardHost-Pathogen Interactions in Tuberculosis Laboratory, Francis Crick Institute, London, United Kingdom.
Maximiliano G GutierrezHost-Pathogen Interactions in Tuberculosis Laboratory, Francis Crick Institute, London, United Kingdom.
The Francis Crick Institute · GB

Funding

Medical Research Council MC_UP_1202/11Wellcome Trust
6 · The paper itself

Abstract

Strict spatiotemporal control of trafficking events between organelles is critical for maintaining homeostasis and directing cellular responses. This regulation is particularly important in immune cells for mounting specialized immune defenses. By controlling the formation, transport and fusion of intracellular organelles, Rab GTPases serve as master regulators of membrane trafficking. In this review, we discuss the cellular and molecular mechanisms by which Rab GTPases regulate immunity and inflammation.

Indexed as

ImmunityAdaptive ImmunityAnimalsAutophagyExocytosisHomeostasisHumansImmune System DiseasesImmunity, InnateInflammationMacrophagesPhagosomesProtein Transportrab GTP-Binding ProteinsSecretory Vesiclesrab GTP-Binding Proteinsinflammationinnate immunitymacrophagesphagosomesRab GTPase

Identifiers

PMID29034219
PMCPMC5627064
OpenAlexW2759908139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.