Evidence map›Paper›PMID 29034173›Full record

ArticleIDCases2017

Mycobacteria Bovis osteomyelitis following intravesical BCG for bladder cancer.

Karan Seegobin, Satish Maharaj, Cherisse Baldeo, Carmen Isache, Bharatsinh Gharia, Lara Zuberi

Open access · goldAbstract readCase Reports
In one paragraph

Article in IDCases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Open forum infectious diseases · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karan SeegobinDepartment of Internal Medicine, University of Florida College of Medicine, Jacksonville, FL, USA.
Satish MaharajDepartment of Internal Medicine, University of Florida College of Medicine, Jacksonville, FL, USA.
Cherisse BaldeoDepartment of Internal Medicine, University of Florida College of Medicine, Jacksonville, FL, USA.
Carmen IsacheDepartment of Infectious Disease, University of Florida College of Medicine, Jacksonville, FL, USA.
Bharatsinh GhariaDepartment of Hematology and Oncology, University of Florida College of Medicine, Jacksonville, FL, USA.
Lara ZuberiDepartment of Hematology and Oncology, University of Florida College of Medicine, Jacksonville, FL, USA.
Florida College · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycobacteria Bovis osteomyelitis is a rare adverse effect after Bacillus Calmette-Guerin (BCG) intravesical therapy. A 62-year-old male presented with acute spinal cord compression three months after completing his second course of therapy for bladder cancer. The first course with intravesical BCG was complicated with an episode of hematuria. He reported intermittent subjective fever for 3 weeks thereafter which resolved with Tylenol. Interferon-α2 B was added to the second cycle of intravesical BCG with the indication here being residual tumor, and was tolerated well. His complete blood count and liver function tests were unremarkable on admission. MRI showed features of osteomyelitis with cord compression at T4/T5. Biopsy of the affected bone showed caseating granuloma which was positive for acid fact bacilli, later confirmed to be Mycobacterium Bovis by PCR and pyrazinamide resistance. He was started on intravenous steroids and underwent spinal cord decompression. Rifampin, Isoniazid, and Ethambutol were then commenced. His weakness improved and after two months of therapy he was asymptomatic and back to his baseline function. Osteomyelitis is a rare but serious complication. Early diagnosis and treatment is important as the outcomes are good.

Indexed as

Intravesical BCGMycobacteria bovisSpinal osteomyelitis

Identifiers

PMID29034173
PMCPMC5635337
OpenAlexW2760463511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.