Evidence map›Paper›PMID 29034089›Full record

ReviewF1000Research2017

More than meets the IR: the expanding roles of variant Ionotropic Glutamate Receptors in sensing odor, taste, temperature and moisture.

Lena van Giesen, Paul A Garrity

Abstract readReview
In one paragraph

Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

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  6. Genome-Wide Identification and Evolutionary Analysis ofAnimals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lena van GiesenNational Center for Behavioral Genomics and Volen Center for Complex Systems Department of Biology, Brandeis University, Waltham, Massachusetts, USA.
Paul A GarrityNational Center for Behavioral Genomics and Volen Center for Complex Systems Department of Biology, Brandeis University, Waltham, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8274-6564

Funding

PROJECT 4: MOLECULAR AND CELLULAR MECHANISMS FOR THERMAL ROBUSTNESS AND MULTISENP01GM103770 · NIGMS · BRANDEIS UNIVERSITY · PI GARRITY, PAUL · 2013 to 2017
$6.2M
Unraveling the polymodal behavior of sensory transduction receptorsR01AI122802 · NIAID · BRANDEIS UNIVERSITY · PI GARRITY, PAUL · 2016 to 2020
$2.3M
NIAID NIH HHS R01 AI122802NIGMS NIH HHS P01 GM103770
6 · The paper itself

Abstract

The ionotropic receptors (IRs) are a branch of the ionotropic glutamate receptor family and serve as important mediators of sensory transduction in invertebrates. Recent work shows that, though initially studied as olfactory receptors, the IRs also mediate the detection of taste, temperature, and humidity. Here, we summarize recent insights into IR evolution and its potential ecological significance as well as recent advances in our understanding of how IRs contribute to diverse sensory modalities.

Indexed as

evolutionary geneticsionotropic receptorssensory perception

Identifiers

PMID29034089
PMCPMC5615767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.