Evidence map›Paper›PMID 29033946›Full record

ArticleFrontiers in immunology2017

Exploitation of Scavenger Receptor, Macrophage Receptor with Collagenous Structure, by

Jintao Xu, Adam Flaczyk, Lori M Neal, Zhenzong Fa, Daphne Cheng, Mike Ivey, Bethany B Moore, Jeffrey L Curtis, John J Osterholzer, Michal A Olszewski

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Dendritic Cells: Multifunctional Roles in Host Defenses toJournal of fungi (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Article
  7. TNF-α-ProducingFrontiers in immunology · 2019
    Article
  8. Interactions of Cryptococcus with Dendritic Cells.Journal of fungi (Basel, Switzerland) · 2018
    Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jintao XuDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
Adam FlaczykDepartment of Veterans Affairs Health System, VA Ann Arbor Healthcare System (VHA), Ann Arbor, MI, United States.
Lori M NealDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
Zhenzong FaDepartment of Veterans Affairs Health System, VA Ann Arbor Healthcare System (VHA), Ann Arbor, MI, United States.
Daphne ChengDepartment of Veterans Affairs Health System, VA Ann Arbor Healthcare System (VHA), Ann Arbor, MI, United States.
Mike IveyDepartment of Veterans Affairs Health System, VA Ann Arbor Healthcare System (VHA), Ann Arbor, MI, United States.
Bethany B MooreDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
Jeffrey L CurtisDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
John J OsterholzerDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
Michal A OlszewskiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, United States.
Michigan Medicine · USVA Ann Arbor Healthcare System · US

Funding

PULMONARY CELLULAR AND MOLECULAR BIOLOGY TRAININGT32HL007749 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 1993 to 2026
$19.9M
miR-29b and autophagy regulate alveolar macrophage function post-BMTR01AI117229 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2015 to 2019
$2.2M
Post Viral Bacterial Pneumonia: Role of MicroRNA and AutophagyR01HL119682 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2014 to 2017
$1.5M
HSCT-induced alterations in DCs to promote IL-17 and lung pathologyR01HL127805 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOORE, BETHANY B. · 2016 to 2018
$1.5M
Modulation of Steroid Suppression by Alveolar Macrophage EfferocytosisI01CX000911 · VA · VETERANS HEALTH ADMINISTRATION · PI CURTIS, JEFFREY LOUIS · 2016 to 2020
–
BLR&D Research Career Scientist Award ApplicationIK6BX003615 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2017 to 2021
–
Modulation of Pulmonary Defenses in Pathobiology of Chronic InfectionsI01BX000656 · VA · VETERANS HEALTH ADMINISTRATION · PI OLSZEWSKI, MICHAL A · 2011 to 2025
–
Recruited Lung Dendritic Cells and the Orchestration of Local Immune ResponsesI01BX002120 · VA · VETERANS HEALTH ADMINISTRATION · PI OSTERHOLZER, JOHN · 2014 to 2019
–
BLRD VA I01 BX000656BLRD VA I01 BX002120BLRD VA IK6 BX003615CSRD VA I01 CX000911NHLBI NIH HHS R01 HL119682NHLBI NIH HHS R01 HL127805NHLBI NIH HHS T32 HL007749NIAID NIH HHS R01 AI117229
6 · The paper itself

Abstract

Macrophage receptor with collagenous structure (MARCO) contributes to fungal containment during the early/innate phase of cryptococcal infection; however, its role in adaptive antifungal immunity remains unknown. Using a murine model of cryptococcosis, we compared host adaptive immune responses in wild-type and MARCO

Indexed as

CD11b+ conventional DCCryptococcus neoformansfungal persistencescavenger receptor macrophage receptor with collagenous structureTh2 response

Identifiers

PMID29033946
PMCPMC5624996
OpenAlexW2758475711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.