Evidence map›Paper›PMID 29033902›Full record

ArticleFrontiers in microbiology2017

Analyzing the Complex Regulatory Landscape of Hfq - an Integrative, Multi-Omics Approach.

Lucia Grenga, Govind Chandra, Gerhard Saalbach, Carla V Galmozzi, Günter Kramer, Jacob G Malone

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Review
  8. Comparative Integrated Omics Analysis of the Hfq Regulon inInternational journal of molecular sciences · 2019
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Lucia GrengaDepartment of Molecular Microbiology, John Innes CentreNorwich, United Kingdom.
Govind ChandraDepartment of Molecular Microbiology, John Innes CentreNorwich, United Kingdom.
Gerhard SaalbachDepartment of Molecular Microbiology, John Innes CentreNorwich, United Kingdom.
Carla V GalmozziCenter for Molecular Biology of the University of Heidelberg, DKFZ-ZMBH AllianceHeidelberg, Germany.
Günter KramerCenter for Molecular Biology of the University of Heidelberg, DKFZ-ZMBH AllianceHeidelberg, Germany.
Jacob G MaloneDepartment of Molecular Microbiology, John Innes CentreNorwich, United Kingdom.
John Innes Centre · GBUniversity of East Anglia · GBDKFZ-ZMBH Alliance · DEHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of bacteria to respond to environmental change is based on the ability to coordinate, redirect and fine-tune their genetic repertoire as and when required. While we can learn a great deal from reductive analysis of individual pathways and global approaches to gene regulation, a deeper understanding of these complex signaling networks requires the simultaneous consideration of several regulatory layers at the genome scale. To highlight the power of this approach we analyzed the Hfq transcriptional/translational regulatory network in the model bacterium

Indexed as

Hfqintegrative approachmulti-omics analysisPseudomonasribosomal profiling

Identifiers

PMID29033902
PMCPMC5627042
OpenAlexW2754005356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.