Evidence map›Paper›PMID 29033612›Full record

ArticleInternational journal of women's health2017

Increased detection of precancerous cervical lesions with adjunctive dynamic spectral imaging.

Sara A DeNardis, Philip T Lavin, Jeff Livingston, William R Salter, Nanette James-Patrick, Emmanouil Papagiannakis, Christopher G Olson, Lori Weinberg

Open access · goldAbstract read
In one paragraph

Article in International journal of women's health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Sara A DeNardisDepartment of Obstetrics/Gynecology, University of Central Florida, Orlando, FL, USA.
Philip T LavinBoston Biostatistics Research Foundation, Framingham, MA, USA.
Jeff LivingstonMacArthur OB/GYN, Irving, TX, USA.
William R SalterAdvanced ObGyn Associates, Richardson, TX, USA.
Nanette James-PatrickSouthwest Women's Healthcare Associates, Olympia Fields, IL, USA.
Emmanouil PapagiannakisDYSIS Medical, Edinburgh, UK.
Christopher G OlsonWomen's Center for Health, Naperville, IL, USA.
Lori WeinbergDepartment of Obstetrics/Gynecology, Advocate Illinois Masonic Medical Center, Chicago, IL, USA.
Advocate Illinois Masonic Medical Center · USJohn D. and Catherine T. MacArthur Foundation · USNational Foundation for Cancer Research · USUniversity of Central Florida · USWomen’s Health Care · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo validate, in US community-based colposcopy clinics, previous reports of increased detection of high-grade cervical intraepithelial neoplasia (CIN2+) with biopsies selected using dynamic spectral imaging (DSI) mapping after standard colposcopy. STUDY

designCross-sectional observational study of 26 colposcopists across nine clinics recruiting consecutive colposcopy patients. Standard assessment with biopsy selections was completed before seeing the DSI map which was subsequently interpreted and used for additional biopsies per clinical judgment. Primary measure was the number of women with CIN2+ detected by DSI-assisted biopsies, over those detected by standard colposcopy biopsies.

resultsA total of 887 women were recruited. After exclusions, 881 women and 1,189 biopsies were analyzed. Standard biopsy detected 78 women with CIN2+ and DSI-assisted biopsies another 34, increasing the detection rate from 8.85% to 12.71% (

conclusionThe largest study, to date, of DSI used in colposcopy confirms previously reported increased detection of CIN2+, across multiple US community-based clinics. Based on the improved efficiency of the DSI-assisted biopsies, this increase suggests an improved diagnostic capacity achieved with DSI and cannot be explained solely by the taking of additional biopsies.

Indexed as

biopsycervix uteriCIN2+colposcopydynamic spectral imaging

Identifiers

PMID29033612
PMCPMC5628669
OpenAlexW2760612246

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.