ArticleActa Cardiologica Sinica2017
Admission Value of Serum Cathepsin D Level Can be Useful for Predicting In-Hospital Mortality in Patients with NSTEMI.
Article in Acta Cardiologica Sinica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Prognostic value of cardiac magnetic resonance-derived myocardial segmental motion curve complexity metrics for recovery ability in post-myocardial infarction patients.Quantitative imaging in medicine and surgery · 2025Article
- Platelet proteome changes in dogs with congestive heart failure.BMC veterinary research · 2020Article
- Article
- Brain Perfusion Matters: From Pituitary Function to Blood Pressure Control during Acute Ischemic Stroke.Acta Cardiologica Sinica · 2018Article
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Authors and funding
8 authors.
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Abstract
backgroundWe aimed to investigate the association of serum cathepsin D levels with in-hospital mortality and Syntax scores (SXscore) in non-ST elevation myocardial infarction (NSTEMI) patients.
methodsA total of 88 patients were included in the study. The patients were divided into two groups: those with in-hospital mortality (-), and those with in-hospital mortality (+). The receiver operating characteristics curve was used to show the sensitivity and specificity of serum cathepsin D levels, and the optimal cut-off value for predicting in-hospital mortality and high SXscore.
resultsPatients with (+) in-hospital mortality and high SXscore had lower serum cathepsin D levels compared to the patients with (-) in-hospital mortality and low SXscore. Using a cutoff score of < 16 for the cathepsin D level, in-hospital mortality was predicted with a sensitivity and specificity of 73.4% and 77.6%, respectively, and also predicted high SXscore with a sensitivity and specificity of 72.4% and 67.6%, respectively.
conclusionsSerum cathepsin D levels established upon admission were significantly and independently lower in NSTEMI patients with high rate of mortality, high SXscores, and low left ventricular ejection fraction.
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