Evidence map›Paper›PMID 29033458›Full record

ArticleThe American biology teacher2017

Creating a Reliable, Cost-Effective ELISA Simulation.

Julie Olson, Michael Amolins, Peter Vitiello

Abstract read
In one paragraph

Article in The American biology teacher, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Julie OlsonScience Teacher at Mitchell High School, 920 N. Capital Street, Mitchell, SD 57301.
Michael AmolinsScience Teacher at Harrisburg High School, PO Box 339, Harrisburg, SD 57032; michael.
Peter VitielloAssistant Scientist at the Children's Health Research Center, Sanford Research, 2301 East 60th Street North, Sioux Falls, SD 57104.

Funding

Sanford Research/USD Science Educator Pediatric Health and Research FellowshipR25HD072596 · NICHD · SANFORD RESEARCH/USD · PI ELLIOTT, AMY J, PEARCE, DAVID A. · 2012 to 2016
$474k
NICHD NIH HHS R25 HD072596
6 · The paper itself

Abstract

The enzyme-linked immunosorbent assay (ELISA) is a fundamental laboratory technique with direct applications across scientific research and clinical diagnostics as well as everyday life. Unfortunately, many challenges exist that inhibit both its introduction and implementation in the high school biology classroom. We present a reliable yet inexpensive way of effectively simulating this assay, allowing student exposure to several advanced topics, including immunodetection, clinical diagnostics, and qualitative and quantitative colorimetric analysis.

Indexed as

biomarkerscolorimetric analysisELISAimmunodetection

Identifiers

PMID29033458
PMCPMC5640158

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.