ArticleAnnals of epidemiology2017
Heart rate variability and lifetime risk of cardiovascular disease: the Atherosclerosis Risk in Communities Study.
Article in Annals of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Heart rate variability as a predictor of stroke course, functional outcome, and medical complications: A systematic review.Frontiers in physiology · 2023Pooled it
- Acute Effects of Resonance Breathing on Skin Sympathetic Nerve Activity and Heart Rate Variability in Healthy Adults.Applied psychophysiology and biofeedback · 2025Trial
- Metabolic and sympathovagal effects of bolus insulin glulisine versus basal insulin glargine therapy in people with type 2 diabetes: A randomized controlled study.Journal of diabetes investigation · 2021Trial
- Trial
- Effects of Walking Football During Ramadan Fasting on Heart Rate Variability and Physical Fitness in Healthy Middle-Aged Males.American journal of men's healthTrial
- Cardiovascular Effects Associated with the Female Athlete Triad: Emerging Evidence Statement from the Female and Male Athlete Triad Coalition.Sports medicine (Auckland, N.Z.) · 2026Review
- Guidelines for rigor and reproducibility of heart rate variability within human cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2026Review
- Arrhythmic risk in axial spondyloarthritis: a narrative review.EULAR rheumatology open · 2026Review
- CoolCuddle and Autonomic Regulation in Infants With Hypoxic-Ischaemic Encephalopathy: An Intervention Study.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Early life stress blunts time-of-day-specific autonomic function in adult male mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- Implementing a Smartphone and Wearable-Based Stress Management Intervention in Women With Coronary Artery Spasms to Reduce Cardiac Symptoms: Multicenter, Single-Arm, 1-Way Crossover Study.JMIR formative research · 2026Article
- Impact of Obstructive Sleep Apnea-Hypopnea Syndrome Severity on Heart Rate Variability and QTc Interval in Hypertensive Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Sleep disruption from inhalation of biomass smoke: a basis for coincident hypertension?Particle and fibre toxicology · 2025Article
- Assessing Minority Stress and Physiological Response Through Ecological Momentary Assessment and Sensors: Protocol for a Feasibility and Acceptability of the Stress and Heart Pilot Study.JMIR formative research · 2025Article
- The Heart-Brain Axis in the Artificial Intelligence Era: Integrating Old and New Insights Towards New Targeting and Innovative Neuro- and Cardio-Therapeutics.International journal of molecular sciences · 2025Review
- Parasympathetic decreases immediately following self-reported cannabis smoking among adults living with cannabis use disorder.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2025Article
- Stress-related genetic factors modify the effect of socioeconomic status on cardiovascular risk.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Higher hemoglobin levels are associated with adverse heart rate variability in a middle-aged birth cohort.Physiological reports · 2025Article
- The Importance of Including Psychophysiological Methods in Psychotherapy.Applied psychophysiology and biofeedback · 2025Review
- Change of heart rate variability in children and adolescent with drug resistant epilepsy.Scientific reports · 2025Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeThe purpose of this study was to estimate the heart rate variability (HRV)-related lifetime cardiovascular disease (CVD) risk.
methodsWe followed 9744 participants without baseline CVD and used a life-table approach to estimate lifetime CVD risk (coronary heart disease, heart failure, and stroke) from 45 through 85 years according to several HRV measures (the SD of RR intervals [SD
resultsDuring 192,110 person-years of follow-up, we documented 2856 CVD events. Cox regression analyses with the false discovery rate method correction showed independent associations of SD
conclusionsGreater HRV was modestly associated with lower lifetime CVD risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.