Evidence map›Paper›PMID 29032776›Full record

ArticleJournal of the International Neuropsychological Society : JINS2018

Neuropsychological Recovery Trajectories in Moderate to Severe Traumatic Brain Injury: Influence of Patient Characteristics and Diffuse Axonal Injury.

Amanda R Rabinowitz, Tessa Hart, John Whyte, Junghoon Kim

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. DTI-derived parameters differ between moderate and severe traumatic brain injury and its association with psychiatric scores.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Amanda R Rabinowitz1Moss Rehabilitation Research Institute,Elkins Park,Pennsylvania.
Tessa Hart1Moss Rehabilitation Research Institute,Elkins Park,Pennsylvania.
John Whyte1Moss Rehabilitation Research Institute,Elkins Park,Pennsylvania.
Junghoon Kim1Moss Rehabilitation Research Institute,Elkins Park,Pennsylvania.

Funding

A Longitudinal Multi-modal Neuroimaging Investigation of Functional Recovery afteR01NS065980 · NINDS · CITY COLLEGE OF NEW YORK · PI KIM, JUNGHOON JOHN · 2011 to 2015
$1.4M
NINDS NIH HHS R01 NS065980
6 · The paper itself

Abstract

objectivesThe goal of the present study was to elucidate the influence of demographic and neuropathological moderators on the longitudinal trajectory neuropsychological functions during the first year after moderate to severe traumatic brain injury (TBI). In addition to examining demographic moderators such as age and education, we included a measure of whole-brain diffuse axonal injury (DAI), and examined measures of processing speed (PS), executive function (EF), and verbal learning (VL) separately.

methodsForty-six adults with moderate to severe TBI were examined at 3, 6, and 12 months post-injury. Participants underwent neuropsychological evaluation and neuroimaging including diffusion tensor imaging. Using linear mixed effects modeling, we examined longitudinal trajectories and moderating factors of cognitive outcomes separately for three domains: PS, VL, and EF.

resultsVL and EF showed linear improvements, whereas PS exhibited a curvilinear trend characterized by initial improvements that plateaued or declined, depending on age. Age moderated the recovery trajectories of EF and PS. Education and DAI did not influence trajectory but were related to initial level of functioning for PS and EF in the case of DAI, and all three cognitive domains in the case of education.

conclusionsWe found disparate recovery trajectories across cognitive domains. Younger age was associated with more favorable recovery of EF and PS. These findings have both clinical and theoretical implications. Future research with a larger sample followed over a longer time period is needed to further elucidate the factors that may influence cognitive change over the acute to chronic period after TBI. (JINS, 2018, 24, 237-246).

Indexed as

AdultAge FactorsBrainBrain Injuries, TraumaticDiffuse Axonal InjuryDiffusion Tensor ImagingEducational StatusExecutive FunctionFemaleGlasgow Coma ScaleHumansMagnetic Resonance ImagingMaleNeuroimagingNeuropsychological TestsRecovery of FunctionBrain injuryCognitionDiffusion tensor imagingExecutive functionNeuropsychological testsVerbal learning

Identifiers

PMID29032776
PMCPMC5957498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.