Evidence map›Paper›PMID 29032478›Full record

ArticleInternational orthopaedics2018

Total knee arthroplasty in patients with a history of illicit intravenous drug abuse.

David E Bauer, Andreas Hingsammer, Lukas Ernstbrunner, Alexander Aichmair, Andrea B Rosskopf, Franziska Eckers, Karl Wieser, Sandro F Fucentese

Abstract read
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Article in International orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Outcomes of medicaid patients undergoing TJA with previous positive urine toxicology screens.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023
    Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Systematic Review of Care Needs for Surgical Patients with Chronic Opioid Use.Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

David E BauerDepartment of Orthopaedics, Balgrist University Hospital, University of Zurich, 8008, Zurich, Switzerland. dudi.bauer@gmail.com.
Andreas HingsammerDepartment of Orthopaedics, Balgrist University Hospital, University of Zurich, 8008, Zurich, Switzerland.
Lukas ErnstbrunnerDepartment of Orthopaedics, Balgrist University Hospital, University of Zurich, 8008, Zurich, Switzerland.
Alexander AichmairDepartment of Orthopaedics, Balgrist University Hospital, University of Zurich, 8008, Zurich, Switzerland.
Andrea B RosskopfDepartment of Radiology, Balgrist University Hospital, University of Zurich, 8008, Zurich, Switzerland.
Franziska EckersDepartment of Orthopaedics, Balgrist University Hospital, University of Zurich, 8008, Zurich, Switzerland.
Karl WieserDepartment of Orthopaedics, Balgrist University Hospital, University of Zurich, 8008, Zurich, Switzerland.
Sandro F FucenteseDepartment of Orthopaedics, Balgrist University Hospital, University of Zurich, 8008, Zurich, Switzerland.
Universitätsklinik Balgrist · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInjection drug users are at high risk for both infection with blood-borne pathogens, namely, human immune deficiency virus (HIV), hepatitis-B, -C virus, various bacterial infections, as well as early primary and secondary joint degeneration. When total knee arthroplasty (TKA) is anticipated the risk of septic complications is a major concern. The purpose of this study was to assess the clinical and radiographic outcome of patients with a history of intravenous drug use after total knee arthroplasty. The primary outcome was revision rate. Secondary outcomes were the Western Ontario and McMaster Universities Arthritis Index (WOMAC), Knee Society Score (KSS) and radiographic loosening.

methodsWe retrospectively reviewed the records of 1,692 TKA performed or revised in our institution. Data of 18 TKA in 12 patients (11 male, 1 female; average age 42, range 23-62 years) with a history of intravenous opioid abuse were available for final analysis.

resultsThe mean follow up was 125 (range 25-238) months. Seven patients required revision surgery due to periprosthetic joint infection after 62 months (range 5-159): one two staged revision, three arthrodesis and three amputations. The median prosthesis survival was 101 (95%-CI 48-154) months.

conclusionTotal knee arthroplasty in patients with a history of intravenous drug abuse is associated with major complications, including above-the-knee amputation. If permanent abstinence from intravenous drug abuse is doubtful, other therapeutic options including primary arthrodesis should be considered.

Indexed as

AdultAmputation, SurgicalArthrodesisArthroplasty, Replacement, KneeFemaleFollow-Up StudiesHumansKnee JointKnee ProsthesisMaleMiddle AgedOpioid-Related DisordersProsthesis FailureProsthesis-Related InfectionsReoperationRetrospective StudiesDrugIntravenousPeriprosthetic joint infection (PJI)Risk factorTotal knee arthroplasty (TKA)

Identifiers

PMID29032478
OpenAlexW2761326878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.