Evidence map›Paper›PMID 29032394›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Clinical performance of

Benedikt Kranzbühler, Hannes Nagel, Anton S Becker, Julian Müller, Martin Huellner, Paul Stolzmann, Urs Muehlematter, Matthias Guckenberger, Philipp A Kaufmann, Daniel Eberli and 1 more

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. European journal of nuclear medicine and molecular imaging · 2022
    Pooled it
  3. PET/MRI in prostate cancer: a systematic review and meta-analysis.European journal of nuclear medicine and molecular imaging · 2021
    Pooled it
  4. Metaanalysis ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Pooled it
  5. Trial
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. The Diagnostic Performance ofIranian journal of public health · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. The role of [European journal of nuclear medicine and molecular imaging · 2023
    Article
  16. SkeletalTherapeutic advances in medical oncology · 2023
    Article
  17. Review
  18. Review of imaging techniques for evaluating morphological and functional responses to the treatment of bone metastases in prostate and breast cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  19. Diagnostic Performance and Clinical Impact ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  20. Cancers · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Benedikt KranzbühlerDepartment of Urology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Hannes NagelDepartment of Nuclear Medicine, University Hospital Zürich, University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland.
Anton S BeckerDepartment of Radiology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Julian MüllerDepartment of Nuclear Medicine, University Hospital Zürich, University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland.
Martin HuellnerDepartment of Nuclear Medicine, University Hospital Zürich, University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland.
Paul StolzmannDepartment of Nuclear Medicine, University Hospital Zürich, University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland.
Urs MuehlematterDepartment of Nuclear Medicine, University Hospital Zürich, University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland.
Matthias GuckenbergerDepartment of Radiation Oncology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Philipp A KaufmannDepartment of Nuclear Medicine, University Hospital Zürich, University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland.
Daniel EberliDepartment of Urology, University Hospital Zürich, University of Zürich, Zürich, Switzerland.
Irene A BurgerDepartment of Nuclear Medicine, University Hospital Zürich, University of Zürich, Rämistrasse 100, 8091, Zürich, Switzerland. Irene.burger@usz.ch.
University of Zurich · CHUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSensitive visualization of recurrent prostate cancer foci is a challenge in patients with early biochemical recurrence (EBR). The recently established

methodsWe retrospectively analyzed a cohort of 56 consecutive patients who underwent a

resultsOverall, in 44 of 56 patients (78.6%) PSMA-positive lesions were detected. In four of nine patients (44.4%) with a PSA < 0.2 ng/mL, suspicious lesions were detected (two pelvic and one paraaortic lymph nodes, and two bone metastases). In eight of 11 patients (72.7%) with a PSA between 0.2 and < 0.5 ng/mL, suspicious lesions were detected (two local recurrences, six lymph nodes, and one bone metastasis). Five out of 20 patients with a PSA < 0.5 ng/mL had extrapelvic disease. In 12 of 15 patients (80.0%) with a PSA between 0.5 and < 2.0 ng/mL, suspicious lesions were detected (four local recurrences, nine lymph nodes, and four bone metastases). In 20 of 21 patients (95.2%) with a PSA >2.0 ng/mL, suspicious lesions were detected. The overall interreader agreement for cancer detection was excellent (κ = 0.796, CI 0.645-0.947).

conclusionsOur data show that

Indexed as

OligopeptidesRadiopharmaceuticalsAgedAged, 80 and overEdetic AcidGallium IsotopesGallium RadioisotopesHumansMagnetic Resonance ImagingMaleMiddle AgedMultimodal ImagingNeoplasm Recurrence, LocalPositron-Emission TomographyProstatic NeoplasmsEdetic Acidgallium 68 PSMA-11Gallium IsotopesGallium RadioisotopesOligopeptidesRadiopharmaceuticals68Ga-PSMA-11Positron emission tomographyProstate cancerProstate-specific antigenPSMA antigen

Identifiers

PMID29032394
OpenAlexW2762330224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.