ArticleMedical science monitor : international medical journal of experimental and clinical research2017
Analysis of Correlation Between Vertebral Endplate Change and Lumbar Disc Degeneration.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Incidence and risk factors for modic changes in the lumbar spine: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Prevalence and distribution of Modic Changes and association with low back pain : a descriptive analysis.Bone & joint open · 2025Article
- Adolescent lumbar disc herniation: etiology, diagnosis, and treatment options.Journal of orthopaedic surgery and research · 2025Review
- New-Occurrence of Postoperative Modic Changes and Its Influence on the Surgical Prognosis After Percutaneous Endoscopic Lumbar Disc Discectomy.Orthopaedic surgery · 2025Article
- Article
- Development of Modic Changes After Percutaneous Endoscopic Transforaminal Lumbar Discectomy: From Risk Analysis to Prediction Modeling.Journal of pain research · 2024Article
- Finite element mechanical analysis of ipsilateral approach and contralateral approach in unilateral bilateral endoscopic spine surgery.Journal of orthopaedic surgery and research · 2023Article
- Epidemiology of Lumbar Degenerative Phenotypes of Children and Adolescents: A Large-Scale Imaging Study.Global spine journal · 2023Article
- Study of the Distribution of Lumbar Modic Changes in Patients with Low Back Pain and Correlation with Lumbar Degeneration Diseases.Journal of pain research · 2023Article
- Forecast of pain degree of lumbar disc herniation based on back propagation neural network.Open life sciences · 2023Article
- Article
- TELD with limited foraminoplasty has potential biomechanical advantages over TELD with large annuloplasty: an in-silico study.BMC musculoskeletal disorders · 2021Article
- Nomograms for Predicting Recurrent Herniation in PETD with Preoperative Radiological Factors.Journal of pain research · 2021Article
- Accurate prediction of lumbar microdecompression level with an automated MRI grading system.Skeletal radiology · 2021Article
- Significant Association between the T2 Values of Vertebral Cartilage Endplates and Pfirrmann Grading.Orthopaedic surgery · 2020Article
- Correlation between the HIF-1α/Notch signaling pathway and Modic changes in nucleus pulposus cells isolated from patients with low back pain.BMC musculoskeletal disorders · 2020Article
- Modic changes of the lumbar spine-their association with the lumbar sagittal parameters: A retrospective imaging study.Journal of orthopaedic surgery and research · 2020Article
- Article
- Indications Selection for Surgeons Training in the Translaminar Percutaneous Endoscopic Discectomy Based on Finite Element Analysis.BioMed research international · 2020Article
- Inhibition of EZH2 ameliorates cartilage endplate degeneration and attenuates the progression of intervertebral disc degeneration via demethylation of Sox-9.EBioMedicine · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND To evaluate the correlation between vertebral endplate change and the level of lumbar disc degeneration via magnetic resonance imaging (MRI). MATERIAL AND METHODS A total of 345 patients who were recruited from our hospital from May 2012 to May 2016 were evaluated for the presence of intervertebral disc degeneration or herniation. The degree of degeneration was assessed according to Pfirrmann grade. Vertebral endplate change was evaluated based on the endplate concave angle (ECA), and Modic change on sagittal MRI. The correlation between ECA and lumbar disc degeneration or Modic change and lumbar disc degeneration was analyzed. RESULTS The results showed that there was no statistically significant difference in comparison of the ECAs in adjacent L3-5 vertebra between males and females. With the aggravation in degenerative changes of L3-5 discs, the ECAs of adjacent L3 superior endplate, L4 inferior and superior endplates and L5 inferior endplate were gradually enlarged, indicating the positive correlation between the lumbar disc degeneration and ECAs. The rate of Modic change in females was higher than that in males without a statistically significant difference. Area of Modic change was positively correlated with the degree of lumbar disc degeneration. Additionally, we also identified the positive correlation between the rate of Modic change and the degree of lumbar disc degeneration. CONCLUSIONS Endplate angle and lumbar disc degeneration are positively correlated. The endplates and endplate signal changes can reflect the degree of disc degeneration and Modic changes can reflect the rate of clinical lumbar disc degeneration degree.
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