ArticleJournal of communication disorders2017
Vocalic transitions as markers of speech acoustic changes with STN-DBS in Parkinson's Disease.
Article in Journal of communication disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Speech and Deep Brain Stimulation in Parkinson's Disease, Essential Tremor, and Dystonia: A Systematic Review and Meta-analysis.Movement disorders : official journal of the Movement Disorder Society · 2026Pooled it
- Speech, voice, and language outcomes following deep brain stimulation: A systematic review.PloS one · 2024Pooled it
- Paired-Comparison Versus Cross-Sectional Approaches for Assessing Longitudinal Speech Change in Parkinson's Disease Following Deep Brain Stimulation of the Subthalamic Nucleus.American journal of speech-language pathology · 2026Article
- No differential effects of subthalamic nucleus vs. globus pallidus deep brain stimulation in Parkinson's disease: Speech acoustic and perceptual findings.IBRO neuroscience reports · 2024Article
- Effects of Deep-Brain Stimulation on Speech: Perceptual and Acoustic Data.Journal of speech, language, and hearing research : JSLHR · 2024Article
- A neurocomputational view of the effects of Parkinson's disease on speech production.Frontiers in human neuroscience · 2024Article
- Singing and Speaking Ability in Parkinson's Disease and Spinocerebellar Ataxia.Journal of speech, language, and hearing research : JSLHR · 2023Article
- Vowel production: a potential speech biomarker for early detection of dysarthria in Parkinson's disease.Frontiers in psychology · 2023Article
- The efficacy of acoustic-based articulatory phenotyping for characterizing and classifying four divergent neurodegenerative diseases using sequential motion rates.Journal of neural transmission (Vienna, Austria : 1996) · 2022Article
- Speech dysfunction, cognition, and Parkinson's disease.Progress in brain research · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purposeDeep Brain Stimulation of the subthalamic nucleus (STN-DBS) effectively treats cardinal symptoms of idiopathic Parkinson's disease (PD) that cannot be satisfactorily managed with medication. Research is equivocal regarding speech changes associated with STN-DBS. This study investigated the impact of STN-DBS on vocalic transitions and the relationship to intelligibility.
methodsEight Quebec-French speakers with PD and eight healthy controls participated. The slope of the second formant frequency (F2 slope) for glides was obtained. Locus equations (LEs) were calculated to capture vocalic transitions in consonant-vowel sequences. A visual analog scale was used to obtain judgments of intelligibility. Measures for the PD group were obtained both On and Off stimulation.
resultsF2 slopes and LEs differed among groups, but there were no systematic differences for On versus Off STN-DBS. On an individual level, participants with PD exhibited heterogeneous changes with DBS stimulation. Intelligibility was significantly correlated with F2 slope.
conclusionF2 slope appears to be sensitive to articulatory impairment in PD and could be used in clinical settings to distinguish these speakers from healthy controls. However, acoustic metrics failed to identify systematic change with STN-DBS. The heterogeneity of results, as well as the clinical relevance of acoustic metrics are discussed.
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