ArticleMolecular metabolism2017
Brown adipocytes can display a mammary basal myoepithelial cell phenotype in vivo.
Article in Molecular metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Mammary adipocyte plasticity and epithelial crosstalk: roles in development, remodeling, and disease.Reviews in endocrine & metabolic disorders · 2026Review
- Reexamining Fat: Exploring Diversity, Plasticity, Development, Functional Implication, and Therapeutic Options.International journal of molecular sciences · 2026Review
- YTHDC1 promotes postnatal brown adipose tissue development and thermogenesis by stabilizing PPARγ.The EMBO journal · 2025Article
- No UCP1 in the kidney.Molecular metabolism · 2025Article
- The Different Shades of Thermogenic Adipose Tissue.Current obesity reports · 2024Review
- Article
- Whitening of brown adipose tissue inhibits osteogenic differentiation via secretion of S100A8/A9.iScience · 2024Article
- Browning of Mammary Fat Suppresses Pubertal Mammary Gland Development of Mice via Elevation of Serum Phosphatidylcholine and Inhibition of PI3K/Akt Pathway.International journal of molecular sciences · 2023Article
- Obese Adipocytes Have Altered Redox Homeostasis with Metabolic Consequences.Antioxidants (Basel, Switzerland) · 2023Review
- Fur removal promotes an earlier expression of involution-related genes in mammary gland of lactating mice.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2023Article
- WTAP regulates postnatal development of brown adipose tissue by stabilizing METTL3 in mice.Life metabolism · 2022Article
- Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis.Nature metabolism · 2022Article
- Sexual Dimorphism in Brown Adipose Tissue Activation and White Adipose Tissue Browning.International journal of molecular sciences · 2022Review
- Article
- Brown adipose tissue is the key depot for glucose clearance in microbiota depleted mice.Nature communications · 2021Article
- Mammary gland adipocytes in lactation cycle, obesity and breast cancer.Reviews in endocrine & metabolic disorders · 2021Review
- The Importance of Breast Adipose Tissue in Breast Cancer.International journal of molecular sciences · 2020Review
- METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice.Nature communications · 2020Article
- Article
- Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePrevious work has suggested that white adipocytes may also show a mammary luminal secretory cell phenotype during lactation. The capacity of brown and beige/brite adipocytes to display a mammary cell phenotype and the levels at which they demonstrate such phenotypes in vivo is currently unknown.
methodsTo investigate the putative adipocyte origin of mammary gland cells, we performed genetic lineage-labeling experiments in BAT and the mammary glands.
resultsThese studies indicated that the classic brown adipocytes (Ucp1
conclusionsThe identification of a brown adipocyte origin of mammary myoepithelial cells provides a novel perspective on the interrelationships between adipocytes and mammary cells with implications for our understanding of obesity and breast cancer.
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Registered trials
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