Evidence map›Paper›PMID 29031577›Full record

ReviewNeuropharmacology2018

Structural biology of GABA

Aurel Frangaj, Qing R Fan

Abstract readReview
In one paragraph

Review in Neuropharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
  2. Article
  3. GABAMedComm · 2025
    Review
  4. Genetic implication of GABAFrontiers in pharmacology · 2025
    Review
  5. Article
  6. Review
  7. Novel-Type GABAACS medicinal chemistry letters · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Sigma-1 receptor and seizures.Pharmacological research · 2023
    Review
  12. Review
  13. Article
  14. Review
  15. The role of GABAFrontiers in endocrinology · 2023
    Review
  16. Neuropharmacology Potential of the Hydroalcoholic Extract from the Leaves ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  17. Review
  18. GABACurrent neuropharmacology · 2022
    Review
  19. Article
  20. CaInternational journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aurel FrangajDepartment of Pharmacology, Columbia University, New York, NY 10032, USA.
Qing R FanDepartment of Pharmacology, Columbia University, New York, NY 10032, USA; Department of Pathology & Cell Biology, Columbia University, New York, NY 10032, USA. Electronic address: qf13@cumc.columbia.edu.

Funding

Structural Analysis of Alcohol-dependent Activation of GIRKsR01AA018734 · NIAAA · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Paul A Slesinger · 2010 to 2026
$6.6M
Mechanism of activation and modulation in human GABA(B) receptorR01GM125801 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FAN, QING R, QUICK, MATTHIAS · 2018 to 2021
$1.7M
Structural Studies of Metabotropic GABA ReceptorsR01GM088454 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FAN, QING R · 2009 to 2015
$1.6M
Structural studies of human extracellular calcium-sensing receptorR01GM112973 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FAN, QING R · 2015 to 2018
$1.3M
NIAAA NIH HHS R01 AA018734NIGMS NIH HHS R01 GM088454NIGMS NIH HHS R01 GM112973NIGMS NIH HHS R01 GM125801
6 · The paper itself

Abstract

Metabotropic GABA

Indexed as

HumansProtein ConformationReceptors, GABA-BReceptors, GABA-BActivationGABA(B) receptorG protein-coupled receptorHeterodimerLigand recognitionStructure

Identifiers

PMID29031577
PMCPMC5897222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.