Evidence map›Paper›PMID 29031186›Full record

ArticleJournal of affective disorders2018

Family functioning as perceived by parents and young offspring at high and low risk for depression.

Shimrit Daches, Vera Vine, Kathryn M Layendecker, Charles J George, Maria Kovacs

Abstract read
In one paragraph

Article in Journal of affective disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  6. Hispanic adolescents' internalizing symptoms and positive family functioning: A bidirectional examination of associations over time.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Family Functioning in Families Affected by Parental Mental Illness: Parent, Child, and Clinician Ratings.International journal of environmental research and public health · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shimrit DachesDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. Electronic address: dachess@pitt.edu.
Vera VineDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Kathryn M LayendeckerDepartment of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Charles J GeorgeDepartment of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Maria KovacsDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

CLINICAL RESEARCH TRAINING IN CHILD PSYCHIATRYT32MH018951 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TINA R GOLDSTEIN · 1990 to 2026
$9.7M
Psychiatric outcomes of children at high- and low-risk for depression: follow upR01MH085722 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOVACS, MARIA · 2010 to 2014
$3.3M
NIMH NIH HHS R01 MH085722NIMH NIH HHS T32 MH018951
6 · The paper itself

Abstract

backgroundFamily dysfunction has been proposed as one of the environmental mechanisms whereby risk of depression is transmitted from mothers to their children. Using our sample of offspring at high and low familial risk for depression, we hypothesized that: a) high-risk offspring (n = 79) and their mothers will report more extensive family dysfunction than low-risk offspring (n = 82) and their mothers, b) family dysfunction will predict the extent of offspring's depressive symptoms, and c) family dysfunction will mediate the impact of mother's depression on offspring's depressive symptoms.

methodsThe study enrolled 161 offspring of parents who, in a previous study, were ascertained to have either childhood onset mood disorder or no history of a major psychiatric disorder. Parents completed questionnaires and a clinical interview about themselves, their offspring, and the family, while offspring also completed questionnaires about themselves and the family.

resultsWe found support for all three hypotheses. The significant indirect effect between maternal depression and offspring depressive symptoms was driven primarily by offspring's, but not mothers', reports of family dysfunction. LIMITATIONS: Although our assessment of mother's early history of depression was done in a previous study, it is important to note that our results do not inform about causality because of the present study's cross-sectional nature.

conclusionsThe results highlight the importance of detecting and treating family dysfunction, particularly via offspring report, as one way to lower the risk of depression transmission from mothers to their children.

Indexed as

Family HealthAdultChildChild of Impaired ParentsCross-Sectional StudiesDepressive DisorderFemaleHumansMaleParentsRisk FactorsSurveys and QuestionnairesFamily functioningHigh-risk for depressionMaternal depressionOffspringTransmission mechanisms

Identifiers

PMID29031186
PMCPMC5700005

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.