ArticleJournal of veterinary internal medicine2017
Glutathione Peroxidase Activity, Plasma Total Antioxidant Capacity, and Urinary F2- Isoprostanes as Markers of Oxidative Stress in Anemic Dogs.
Article in Journal of veterinary internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Effects of Blueberry Consumption on Preference, Digestibility, and Oxidative Balance in Dogs.Animals : an open access journal from MDPI · 2025Article
- Case report: Suspected propofol associated Heinz body anemia in five mechanically ventilated dogs: a historical case series.Frontiers in veterinary science · 2025Article
- Article
- Oxidative Stress in Canine Diseases: A Comprehensive Review.Antioxidants (Basel, Switzerland) · 2024Review
- Hemolysis, icterus and lipemia interfere with the determination of two oxidative stress biomarkers in canine serum.BMC veterinary research · 2023Article
- Antioxidant Nanozymes: Mechanisms, Activity Manipulation, and Applications.Micromachines · 2023Review
- Selected biomarkers of oxidative stress in healthy Beagle dogs: A preliminary study.Frontiers in veterinary science · 2023Article
- Peripheral biomarkers of oxidative stress in dogs with acute pancreatitis.Journal of veterinary internal medicine · 2022Article
- Detection of Anti-Erythrocyte Antibodies in Dogs with Inflammatory Bowel Disease (IBD).Animals : an open access journal from MDPI · 2021Article
- Reactive oxygen species, glutathione, and vitamin E concentrations in dogs with hemolytic or nonhemolytic anemia.Journal of veterinary internal medicine · 2020Article
- Assessment of urinary 15-FJournal of veterinary internal medicine · 2020Article
- Biomarkers of oxidative stress as an assessment of the redox status of the liver in dogs.Journal of veterinary internal medicine · 2019Article
- The antioxidant components of milk and their role in processing, ripening, and storage: Functional food.Veterinary world · 2019Article
- Xylanase and Fermented Polysaccharide ofOxidative medicine and cellular longevity · 2018Article
- Effect of N-Acetylcysteine, Ascorbic Acid, and a Vitamin E Analog on Oxidative and Storage Lesions in Canine Packed Red Blood Cells.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)Article
- Potential mechanism for hyperhomocysteinemia in Greyhound dogs.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOxidative stress plays a role in the pathophysiology of several diseases and has been documented as a contributor to disease in both the human and veterinary literature. One at-risk cell is the erythrocyte, however, the role of oxidative stress in anemia in dogs has not been widely investigated. HYPOTHESIS/
objectiveAnemic dogs will have an alteration in the activity of glutathione peroxidase (GPx), a decrease in of total antioxidant capacity (TAC), and an increased concentration of urinary 15-F ANIMALS: 40 client-owned dogs with anemia (PCV <30%) age-matched to 40 client-owned healthy control dogs.
methodsProspective, cross-sectional study. Whole blood GPx activity, plasma TAC, and urinary F
resultsAnemic dogs had significantly lower GPx activity (43.1 × 10 CONCLUSIONS AND CLINICAL IMPORTANCE: Glutathione peroxidase activity was significantly decreased in anemic dogs indicating oxidative stress. Additional studies are warranted to determine if antioxidant supplementation would improve survival and overall outcome as part of a therapeutic regimen for anemic dogs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.