Evidence map›Paper›PMID 29030425›Full record

ArticleThe Journal of biological chemistry2017

Quantitative time-course metabolomics in human red blood cells reveal the temperature dependence of human metabolic networks.

James T Yurkovich, Daniel C Zielinski, Laurence Yang, Giuseppe Paglia, Ottar Rolfsson, Ólafur E Sigurjónsson, Jared T Broddrick, Aarash Bordbar, Kristine Wichuk, Sigurður Brynjólfsson and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Red Blood Cell Storage and Post-transfusion Recovery.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Review
  6. Improved Rat Heart Preservation Using High-Pressure Gaseous Perfusion with Oxygen-Xenon Mixture.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. It's in your blood: The impact of age, sex, genetic factors and exposures on stored red blood cell metabolism.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2024
    Review
  12. Article
  13. Chloride Gradient Is Involved in Ammonium Influx in Human Erythrocytes.International journal of molecular sciences · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Metabolic Oscillations and Glycolytic Phenotypes of Cancer Cells.International journal of molecular sciences · 2023
    Article
  19. Review
  20. Omics Technologies in Veterinary Medicine: Literature Review and Perspectives in Transfusion Medicine.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 7 countries.

James T YurkovichFrom the Departments of Bioengineering and.ORCID 0000-0002-9403-509X
Daniel C ZielinskiFrom the Departments of Bioengineering and.ORCID 0000-0002-2433-4705
Laurence YangFrom the Departments of Bioengineering and.ORCID 0000-0001-6663-7643
Giuseppe PagliaInstitute for Biomedicine, EURAC Research, Viale Druso Drususallee 1, 39100 Bolzano, Bozen, Italy.ORCID 0000-0003-4724-6801
Ottar RolfssonCenter for Systems Biology, University of Iceland, Sturlugata 8, IS-101 Reykjavík, Iceland.ORCID 0000-0003-4258-6057
Ólafur E SigurjónssonThe Blood Bank, Landspítali-University Hospital, Snorrabraut 60, 105 Reykjavík, Iceland.
Jared T BroddrickFrom the Departments of Bioengineering and.ORCID 0000-0003-4871-4822
Aarash BordbarSinopia Biosciences, San Diego, California 92101.
Kristine WichukCenter for Systems Biology, University of Iceland, Sturlugata 8, IS-101 Reykjavík, Iceland.ORCID 0000-0001-5376-1709
Sigurður BrynjólfssonCenter for Systems Biology, University of Iceland, Sturlugata 8, IS-101 Reykjavík, Iceland.
Sirus PalssonCenter for Systems Biology, University of Iceland, Sturlugata 8, IS-101 Reykjavík, Iceland.
Sveinn GudmundssonThe Blood Bank, Landspítali-University Hospital, Snorrabraut 60, 105 Reykjavík, Iceland.
Bernhard O PalssonFrom the Departments of Bioengineering and palsson@ucsd.edu.
University of Iceland · ISLa Jolla Bioengineering Institute · USEurac Research · ITInstitut thématique Génétique, génomique et bioinformatique · FRNational University Hospital of Iceland · ISReykjavík University · ISSinopia Biosciences (United States) · USUniversity of California San Diego · US

Funding

Improving red blood cell transfusion through systems biologyR43HL123074 · NHLBI · SINOPIA BIOSCIENCES, INC. · PI BORDBAR, AARASH · 2014 to 2014
$150k
NHLBI NIH HHS R43 HL123074
6 · The paper itself

Abstract

The temperature dependence of biological processes has been studied at the levels of individual biochemical reactions and organism physiology (

Indexed as

TemperatureErythrocytesGlycolysisHumansIn Vitro TechniquesMetabolomicscomputational biologyerythrocytemetabolismmetabolomicssystems biology

Identifiers

PMID29030425
PMCPMC5712598
OpenAlexW2763014033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.