Evidence map›Paper›PMID 29030342›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2018

Sex-specific impact of aging on the blood pressure response to exercise.

Joel D Trinity, Gwenael Layec, Corey R Hart, Russell S Richardson

Open access · greenAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  15. The exercise pressor reflex: An update.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joel D TrinityGeriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center , Salt Lake City, Utah.
Gwenael LayecDepartment of Internal Medicine, Division of Geriatrics, University of Utah , Salt Lake City, Utah.
Corey R HartDepartment of Nutrition and Integrative Physiology, University of Utah , Salt Lake City, Utah.
Russell S RichardsonGeriatric Research, Education, and Clinical Center, George E. Whalen VA Medical Center , Salt Lake City, Utah.
University of Utah · USLake City VA Medical Center · US

Funding

Tissue Imaging, Biochemistry and MorphologyP01HL091830 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WAGNER, PETER D · 2009 to 2013
$10.1M
Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPDK99HL125756 · NHLBI · UNIVERSITY OF UTAH · PI LAYEC, GWENAEL · 2015 to 2016
$300k
Understanding the Exercise-Hypertension Paradox: Implication for RehabilitationIK2RX001215 · VA · VA SALT LAKE CITY HEALTHCARE SYSTEM · PI TRINITY, JOEL DOUGLAS · 2014 to 2018
–
NHLBI NIH HHS K99 HL125756NHLBI NIH HHS P01 HL091830RRD VA IK2 RX001215
6 · The paper itself

Abstract

An exaggerated blood pressure (BP) response to exercise has been linked to cardiovascular disease, but little is known about the impact of age and sex on this response. Therefore, this study examined the hemodynamic and skeletal muscle metabolic response to dynamic plantar flexion exercise, at 40% of maximum plantar flexion work rate, in 40 physical activity-matched young (23 ± 1 yr, n = 20) and old (73 ± 2 yr, n = 20), equally distributed, male and female subjects. Central hemodynamics and BP (finometer), popliteal artery blood flow (Doppler ultrasound), and skeletal muscle metabolism (

Indexed as

AgingArterial PressureExerciseMuscle ContractionVascular ResistanceAdaptation, PhysiologicalAgedAge FactorsBlood Flow VelocityEnergy MetabolismFemaleHumansMaleMuscle, SkeletalPopliteal ArteryRegional Blood Flowblood flowexercise pressor reflexmagnetic resonance spectroscopymetabolismpopliteal vascular conductancesystemic vascular resistance

Identifiers

PMID29030342
PMCPMC5866392
OpenAlexW2763067220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.