Observational studyThe Journal of urology2018
The Association between Mortality and Distance to Treatment Facility in Patients with Muscle Invasive Bladder Cancer.
Observational study in The Journal of urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed.
- Drive Time to Physicians and Outcomes for Bladder Cancer.JU open plus · 2025Article
- Demystifying delays: Factors associated with timely treatment of adrenocortical carcinoma.American journal of surgery · 2025Article
- Impact of travel distance on short-term outcomes in patients receiving treatment for urolithiasis A population-based study.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025Article
- Income Disparities in Survival and Receipt of Neoadjuvant Chemotherapy and Pelvic Lymph Node Dissection for Muscle-Invasive Bladder Cancer.Current oncology (Toronto, Ont.) · 2024Article
- Impact of rural residence on the presentation, management and survival of patients with non-metastatic muscle-invasive bladder carcinoma.Investigative and clinical urology · 2023Article
- The impact of distance traveled and rurality on the clinical course of head and neck cancer.Laryngoscope investigative otolaryngology · 2023Article
- Long-Term Impact of Medicaid Expansion on Colorectal Cancer Screening in Its Targeted Population.Digestive diseases and sciences · 2023Article
- Retroperitoneal Lymph Node Dissection Versus Surveillance for Adult Early Stage Pure Testicular Teratoma: A Nationwide Analysis.Annals of surgical oncology · 2021Article
- Systematic review of the association between socioeconomic status and bladder cancer survival with hospital type, comorbidities, and treatment delay as mediators.BJUI compass · 2021Review
- Factors Associated With Receipt of Partial Nephrectomy or Minimally Invasive Surgery for Patients With Clinical T1a and T1b Renal Masses: Implications for Regionalization of Care.Clinical genitourinary cancer · 2020Article
- Treatment Patterns and Distance to Treatment Facility for Soft Tissue Sarcoma of the Extremity.The Journal of surgical research · 2020Article
- Predicting salvage laryngectomy in patients treated with primary nonsurgical therapy for laryngeal squamous cell carcinoma using machine learning.Head & neck · 2020Article
- Pathologic measures of quality compare favorably in patients undergoing robot-assisted radical cystectomy to open cystectomy cohorts: a National Cancer Database analysis.Journal of robotic surgery · 2020Article
- Article
- Trends in Regionalization of Care and Mortality For Patients Treated With Radical Cystectomy.Medical care · 2019Observational
- Exploring trends in advanced bladder cancer using the NCDB: turning data into information and information into insight.Translational andrology and urology · 2018Article
- Challenges facing regionalization of radical cystectomy.Translational andrology and urology · 2018Article
- Surviving travel or travelling to survive: the association of travel distance with survival in muscle invasive bladder cancer.Translational andrology and urology · 2018Article
- Clinical benefit to regionalization of care for muscle invasive bladder cancer.Translational andrology and urology · 2018Article
- Downstream effects of regionalization: reconciling our predictions with the volume-outcome paradigm.Translational andrology and urology · 2018Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeRegionalization of bladder cancer treatment is suggested to improve quality of care. As an unintended consequence some patients travel farther for care with unknown implications on outcomes. We characterized the relationship between distance and overall mortality in patients with invasive bladder cancer and those who underwent radical cystectomy. MATERIALS AND
methodsWe performed a retrospective cohort study using NCDB (National Cancer Database) from 2004 to 2012 to identify patients with muscle invasive bladder cancer (cT2a-T4 N0 M0). We also extracted a subgroup of patients who underwent radical cystectomy. Multivariate Cox proportional hazards and multinomial logistic regression analyses were performed in each group, controlling for demographic, clinical, hospital and geographic factors.
resultsFor 34,729 patients with muscle invasive bladder cancer traveling farther for treatment was associated with a lower probability of overall mortality (referent less than 12.5 miles, 12.5 to 49.9 miles HR 0.96, 95% CI 0.92-0.99 and 50 to 249.9 miles HR 0.91, 95% CI 0.86-0.96). This was significant for patients with cT2 disease and those treated at academic centers (p ≤0.05). For 11,059 patients who underwent radical cystectomy this trend did not reach significance. However, longer distance was associated with surgery at a high volume institution and receipt of neoadjuvant chemotherapy (each p <0.001).
conclusionsPatients who traveled farther for bladder cancer treatment did not experience inferior survival outcomes and traveling to academic institutions was associated with reduced mortality. For patients who undergo cystectomy this relationship was equivocal, although longer distance was associated with receiving neoadjuvant chemotherapy or surgery at a high volume facility. These findings may reflect a complex association of regionalization of bladder cancer care with patient individual health and health care seeking behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.