Evidence map›Paper›PMID 29029890›Full record

ArticleInternational journal of radiation oncology, biology, physics2017

Radiation Therapy Deficiencies Identified During On-Site Dosimetry Visits by the Imaging and Radiation Oncology Core Houston Quality Assurance Center.

Stephen F Kry, Lainy Dromgoole, Paola Alvarez, Jessica Leif, Andrea Molineu, Paige Taylor, David S Followill

Abstract read
In one paragraph

Article in International journal of radiation oncology, biology, physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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  5. Quality Assurance in Clinical Trials Requiring Radiation Therapy in Sub-Saharan Africa.International journal of radiation oncology, biology, physics · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stephen F KryImaging and Radiation Oncology Core Quality Assurance Center in Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; The University of Texas Health Science Center Houston, Graduate School of Biomedical Sciences, Houston, Texas. Electronic address: sfkry@mdanderson.org.
Lainy DromgooleImaging and Radiation Oncology Core Quality Assurance Center in Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Paola AlvarezImaging and Radiation Oncology Core Quality Assurance Center in Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Jessica LeifImaging and Radiation Oncology Core Quality Assurance Center in Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Andrea MolineuImaging and Radiation Oncology Core Quality Assurance Center in Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Paige TaylorImaging and Radiation Oncology Core Quality Assurance Center in Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas.
David S FollowillImaging and Radiation Oncology Core Quality Assurance Center in Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas; The University of Texas Health Science Center Houston, Graduate School of Biomedical Sciences, Houston, Texas.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
IROC: Enhancing local enrolling site radiological data capture capabilities for NCTN trialsU24CA180803 · NCI · AMERICAN COLLEGE OF RADIOLOGY · PI Thomas J. FitzGerald, MICHAEL V KNOPP · 2014 to 2026
$116.2M
RADIOLOGICAL PHYSICS CENTERU10CA010953 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI FOLLOWILL, DAVID S · 1985 to 2013
$34.5M
Correcting Dose Calculation Errors in Radiation OncologyR01CA214526 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KRY, STEPHEN F · 2017 to 2020
$594k
NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA214526NCI NIH HHS U10 CA010953NCI NIH HHS U24 CA180803
6 · The paper itself

Abstract

purposeTo review the dosimetric, mechanical, and programmatic deficiencies most frequently observed during on-site visits of radiation therapy facilities by the Imaging and Radiation Oncology Core Quality Assurance Center in Houston (IROC Houston). METHODS AND MATERIALS: The findings of IROC Houston between 2000 and 2014, including 409 institutions and 1020 linear accelerators (linacs), were compiled. On-site evaluations by IROC Houston include verification of absolute calibration (tolerance of ±3%), relative dosimetric review (tolerances of ±2% between treatment planning system [TPS] calculation and measurement), mechanical evaluation (including multileaf collimator and kilovoltage-megavoltage isocenter evaluation against Task Group [TG]-142 tolerances), and general programmatic review (including institutional quality assurance program vs TG-40 and TG-142).

resultsAn average of 3.1 deficiencies was identified at each institution visited, a number that has decreased slightly with time. The most common errors are tabulated and include TG-40/TG-142 compliance (82% of institutions were deficient), small field size output factors (59% of institutions had errors ≥3%), and wedge factors (33% of institutions had errors ≥3%). Dosimetric errors of ≥10%, including in beam calibration, were seen at many institutions.

conclusionsThere is substantial room for improvement of both dosimetric and programmatic issues in radiation therapy, which should be a high priority for the medical physics community. Particularly relevant was suboptimal beam modeling in the TPS and a corresponding failure to detect these errors by not including TPS data in the linac quality assurance process.

Indexed as

CalibrationCancer Care FacilitiesHumansQuality Assurance, Health CareRadiation OncologyRadiometryRadiotherapyRadiotherapy DosageRadiotherapy Setup ErrorsTime Factors

Identifiers

PMID29029890
PMCPMC5699963

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.