ArticleBurns : journal of the International Society for Burn Injuries2018
Burn injury outcomes in patients with pre-existing diabetic mellitus: Risk of hospital-acquired infections and inpatient mortality.
Article in Burns : journal of the International Society for Burn Injuries, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- Survival status and predictors of mortality among burn patients admitted to intensive care units at burn centres in Addis Ababa, Ethiopia: a retrospective follow-up study.International journal of emergency medicine · 2026Article
- Sick Becomes Seriously Ill-Scald Injuries due to Domestic Medical Self-Treatment: A Six-Year Single Center Retrospective Study.International wound journal · 2025Article
- THE EFFECT OF MULTIDRUG-RESISTANT ORGANISM INFECTION ON MORTALITY OF BURN PATIENTS AT RSUPN DR. CIPTO MANGUNKUSUMO.Annals of burns and fire disasters · 2024Article
- [Burns and Diabetes Mellitus: Epidemiology, Clinical Presentation and Prognosis].Annals of burns and fire disasters · 2024Article
- Psychiatric Illness and Substance Abuse: Unaddressed Factors in Burn Injury.Journal of burn care & research : official publication of the American Burn Association · 2023Article
- Re-evaluation of the Effect of Age on In-hospital Burn Mortality in a Resource-Limited Setting.The Journal of surgical research · 2021Article
- Environmental Contamination of Contact Precaution and Non-Contact Precaution Patient Rooms in Six Acute Care Facilities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Outcomes and complications of diabetic burn injuries: a single center experience.International journal of burns and trauma · 2021Article
- Sex-Based Differences in Inpatient Burn Mortality.World journal of surgery · 2019Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundDiabetes mellitus (DM) is a major cause of illness and death in the United States, and diabetic patients are at increased risk for burn injury. We therefore sought to examine the impact of pre-existing DM on the risk of inpatient mortality and hospital acquired infections (HAI) among burn patients.
methodsAdult patients (≥18 years old) admitted from 2004 to 2013 were analyzed. Weighted Kaplan-Meier survival curves - adjusting for patient demographics, burn mechanism, presence of inhalation injury, total body surface area, additional comorbidities, and differential lengths of stay - were used to estimate the 30-day and 60-day risk of mortality and HAIs.
resultsA total of 5539 adult patients were admitted and included in this study during the study period. 655 (11.8%) had a pre-existing DM. The crude incidence of HAIs and in-hospital mortality for the whole burn cohort was 8.5% (n=378) and 4.4% (n=243), respectively. Diabetic patients were more likely to be older, female, have additional comorbidities, inhalational injury, and contact burns. After adjusting for patient and burn characteristics, the 60-day risk of HAI among patients with DM was significantly higher, compared to non-diabetic patients (RR 2.07, 95% CI 1.28, 6.79). However, no significant difference was seen in the 60-day risk of mortality (RR 1.34, 95% CI 0.44, 3.10).
conclusionsPre-existing DM significantly increases the risk of developing an HAI in patients following burn injury, but does not significantly impact the risk of inpatient mortality. Further understanding of the immune modulatory mechanism of burn injury and DM is imperative to better attenuate the acquisition of HAIs.
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