Evidence map›Paper›PMID 29029679›Full record

Trial reportBehavior therapy2017

Investigating Habituation to Premonitory Urges in Behavior Therapy for Tic Disorders.

David C Houghton, Matthew R Capriotti, Lawrence D Scahill, Sabine Wilhelm, Alan L Peterson, John T Walkup, John Piacentini, Douglas W Woods

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Behavior therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06825520 (Investigating Changes in Premonitory Urges During Habit Reversal Training), which is not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06825520 narecruitingnot on this mapstarted 2025, after this paper: background citation

Investigating Changes in Premonitory Urges During Habit Reversal Training

TypeinterventionalSponsorUniversity of UtahRan2025 to 2026Enrolled6ConditionsTics, Tourette Disorder, Tourette Syndrome in Children, Tourette Syndrome in AdolescenceArmsHabit Reversal Training
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Cognitive control processes in behavior therapy for youth with Tourette's disorder.Journal of child psychology and psychiatry, and allied disciplines · 2022
    Trial
  7. Trial
  8. Article
  9. Article
  10. Activation of MBritish journal of pharmacology · 2024
    Article
  11. Article
  12. Article
  13. Sensory Gating in Neurodevelopmental Disorders: A Scoping Review.Research on child and adolescent psychopathology · 2023
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Correlates and clinical implications of tic suppressibility.Current developmental disorders reports · 2021
    Article
  19. A Review of Cognitive and Behavioral Interventions for Tic Disorder.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 1 country.

David C HoughtonTexas A&M University. Electronic address: davidhoughton@tamu.edu.
Matthew R CapriottiSan Jose State University; University of California San Francisco.
Lawrence D ScahillEmory University.
Sabine WilhelmMassachusetts General Hospital/Harvard Medical School.
Alan L PetersonUniversity of Texas Health Science Center at San Antonio.
John T WalkupWeill Cornell Medical College of Cornell University.
John PiacentiniUniversity of California Los Angeles.
Douglas W WoodsMarquette University.
Cornell University · USEmory University · USHarvard University · USMarquette University · USSan Jose State University · USTexas A&M University · USThe University of Texas Health Science Center at San Antonio · USUniversity of California, Los Angeles · US

Funding

Behavior Therapy for Children with Chronic Tic DisordersR01MH070802 · NIMH · TOURETTE SYNDROME ASSOCIATION, INC · PI PIACENTINI, JOHN C. · 2004 to 2007
$2.9M
Behavior Therapy for Adults with Tourette SyndromeR01MH069874 · NIMH · YALE UNIVERSITY · PI SCAHILL, LAWRENCE D. · 2005 to 2009
$1.2M
Behavior Therapy for Adults with Tourette SyndromeR01MH069877 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WILHELM, SABINE · 2005 to 2009
$918k
Behavior Therapy for Adults with Tourette SyndromeR01MH069875 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI PETERSON, ALAN L · 2005 to 2008
$719k
NIMH NIH HHS R01 MH069874NIMH NIH HHS R01 MH069875NIMH NIH HHS R01 MH069877NIMH NIH HHS R01 MH070802
6 · The paper itself

Abstract

Behavior therapy is effective for Persistent Tic Disorders (PTDs), but behavioral processes facilitating tic reduction are not well understood. One process, habituation, is thought to create tic reduction through decreases in premonitory urge severity. The current study tested whether premonitory urges decreased in youth with PTDs (N = 126) and adults with PTDs (N = 122) who participated in parallel randomized clinical trials comparing behavior therapy to psychoeducation and supportive therapy (PST). Trends in premonitory urges, tic severity, and treatment outcome were analyzed according to the predictions of a habituation model, whereby urge severity would be expected to decrease in those who responded to behavior therapy. Although adults who responded to behavior therapy showed a significant trend of declining premonitory urge severity across treatment, results failed to demonstrate that behavior therapy specifically caused changes in premonitory urge severity. In addition, reductions in premonitory urge severity in those who responded to behavior therapy were significant greater than those who did not respond to behavior therapy but no different than those who responded or did not respond to PST. Children with PTDs failed to show any significant changes in premonitory urges. Reductions in premonitory urge severity did not mediate the relationship between treatment and outcome in either adults or children. These results cast doubt on the notion that habituation is the therapeutic process underlying the effectiveness of behavior therapy, which has immediate implications for the psychoeducation and therapeutic rationale presented in clinical practice. Moreover, there may be important developmental changes in premonitory urges in PTDs, and alternative models of therapeutic change warrant investigation.

Indexed as

Habituation, PsychophysiologicAdolescentAdultBehavior TherapyChildFemaleHumansMaleModels, PsychologicalTic DisordersTreatment Outcomebehavior therapyhabituationpsychotherapytics

Identifiers

PMID29029679
PMCPMC5679290
OpenAlexW2742459374

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.