Evidence map›Paper›PMID 29029509›Full record

ArticleOncotarget2017

Establishment of oral squamous cell carcinoma cell line and magnetic bead-based isolation and characterization of its CD90/CD44 subpopulations.

Marketa Svobodova, Martina Raudenska, Jaromir Gumulec, Jan Balvan, Michaela Fojtu, Monika Kratochvilova, Hana Polanska, Zuzana Horakova, Rom Kostrica, Petr Babula and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Marketa SvobodovaDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Martina RaudenskaDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Jaromir GumulecDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Jan BalvanDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Michaela FojtuDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Monika KratochvilovaDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Hana PolanskaDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Zuzana HorakovaDepartment of Otorhinolaryngology and Head and Neck Surgery, St. Anne's Faculty Hospital, CZ-65691 Brno, Czech Republic.
Rom KostricaDepartment of Otorhinolaryngology and Head and Neck Surgery, St. Anne's Faculty Hospital, CZ-65691 Brno, Czech Republic.
Petr BabulaDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Zbynek HegerCentral European Institute of Technology, Brno University of Technology, CZ-61600 Brno, Czech Republic.
Michal MasarikDepartment of Physiology, Faculty of Medicine, Masaryk University, CZ-62500 Brno, Czech Republic.
Masaryk University · CZCentral European Institute of Technology · CZSt. Anne's University Hospital Brno · CZBrno University of Technology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we describe the establishment of the human papillomavirus 18-positive, stage II, grade 1, T2N0M0 head and neck tumor primary cell line derived from oral squamous cell carcinoma of a non-smoking patient by using two different protocols. Furthermore, a preparation of subpopulations derived from this primary cell line according to the cluster of differentiation molecules CD44/CD90 status using magnetic bead-based separation and their characterization was performed. Impedance-based real-time cell analysis, enzyme-linked immunsorbant assay (ELISA), wound-healing assay, flow-cytometry, gene expression analysis, and MTT assay were used to characterize these four subpopulations (CD44

Indexed as

carcinomacell linecoculture techniqueshead and neck neoplasmstumor

Identifiers

PMID29029509
PMCPMC5630409
OpenAlexW2742219714

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.