Evidence map›Paper›PMID 29028872›Full record

ReviewBriefings in bioinformatics2019

A review of methods and databases for metagenomic classification and assembly.

Florian P Breitwieser, Jennifer Lu, Steven L Salzberg

Abstract readReview
In one paragraph

Review in Briefings in bioinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 272 papers.

0numbers the graph read from it
0cells of the map it votes in
272citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

272 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Deconvolving Phylogenetic Distance Mixtures.bioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Detection ofFood chemistry. Molecular sciences · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article

212 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Florian P Breitwieser
Jennifer Lu
Steven L Salzberg

Funding

Computational Methods for Genome Assembly, Transcript Assembly, and Variant DiscoveryR01HG006677 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI SALZBERG, STEVEN L. · 2011 to 2025
$10.7M
Computational Methods for Microbial and Microbiome Sequence AnalysisR35GM130151 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Steven L. Salzberg · 2019 to 2026
$2.9M
Bioinformatics Software for Analyzing Microbial GenomesR01GM083873 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI SALZBERG, STEVEN L. · 2008 to 2017
$2.1M
NHGRI NIH HHS R01 HG006677NIGMS NIH HHS R01 GM083873NIGMS NIH HHS R35 GM130151
6 · The paper itself

Abstract

Microbiome research has grown rapidly over the past decade, with a proliferation of new methods that seek to make sense of large, complex data sets. Here, we survey two of the primary types of methods for analyzing microbiome data: read classification and metagenomic assembly, and we review some of the challenges facing these methods. All of the methods rely on public genome databases, and we also discuss the content of these databases and how their quality has a direct impact on our ability to interpret a microbiome sample.

Indexed as

Databases, GeneticAlgorithmsComputational BiologyGene Expression ProfilingGenetic MarkersHigh-Throughput Nucleotide SequencingMetagenomeMetagenomicsMicrobiotaPhylogenySequence AlignmentGenetic Markersbacteriadatabasesmicrobial genomicsmicrobiomenext-generation sequencing

Identifiers

PMID29028872
PMCPMC6781581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.