ArticleBriefings in functional genomics2018
Global and targeted approaches to single-cell transcriptome characterization.
Article in Briefings in functional genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- The ciliary neurotrophic factor induces Stat3 phosphorylation in distinctive cytotypes of organs involved in body metabolism: An immunohistochemical study.Journal of anatomy · 2026Article
- Transcript Identification Using Arrayed Hydrogels with TrapFISH.Advanced materials technologies · 2025Article
- Single-cell multi-omics in the study of digestive system cancers.Computational and structural biotechnology journal · 2024Review
- Canine Mammary Tumors: Classification, Biomarkers, Traditional and Personalized Therapies.International journal of molecular sciences · 2024Review
- A miR-34a-guided, tRNACell death discovery · 2022Article
- Evidence for close molecular proximity between reverting and undifferentiated cells.BMC biology · 2022Article
- NANOG initiates epiblast fate through the coordination of pluripotency genes expression.Nature communications · 2022Article
- Epigenetic Reprogramming of the Glucose Metabolic Pathways by the Chromatin Effectors During Cancer.Sub-cellular biochemistry · 2022Article
- An improved method for specific-target preamplification PCR analysis of single blastocysts useful for embryo sexing and high-throughput gene expression analysis.Journal of dairy science · 2021Article
- Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells.The Journal of experimental medicine · 2021Article
- Current Achievements and Applications of Transcriptomics in Personalized Cancer Medicine.International journal of molecular sciences · 2021Review
- Evolution of Drug-ResistantFrontiers in microbiology · 2021Review
- Targeted transcript quantification in single disseminated cancer cells after whole transcriptome amplification.PloS one · 2019Article
- Seq-Well: A Sample-Efficient, Portable Picowell Platform for Massively Parallel Single-Cell RNA Sequencing.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Using single cell analysis for translational studies in immune mediated diseases: Opportunities and challenges.Molecular immunology · 2018Review
- Identification of reference genes for circulating long noncoding RNA analysis in serum of cervical cancer patients.FEBS open bio · 2018Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Analysing transcriptomes of cell populations is a standard molecular biology approach to understand how cells function. Recent methodological development has allowed performing similar experiments on single cells. This has opened up the possibility to examine samples with limited cell number, such as cells of the early embryo, and to obtain an understanding of heterogeneity within populations such as blood cell types or neurons. There are two major approaches for single-cell transcriptome analysis: quantitative reverse transcription PCR (RT-qPCR) on a limited number of genes of interest, or more global approaches targeting entire transcriptomes using RNA sequencing. RT-qPCR is sensitive, fast and arguably more straightforward, while whole-transcriptome approaches offer an unbiased perspective on a cell's expression status.
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