Evidence map›Paper›PMID 29028040›Full record

ArticleOptics letters2017

Ex vivo validation of photo-magnetic imaging.

Alex Luk, Farouk Nouizi, Hakan Erkol, Mehmet B Unlu, Gultekin Gulsen

Abstract read
In one paragraph

Article in Optics letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alex Luk
Farouk Nouizi
Hakan Erkol
Mehmet B Unlu
Gultekin Gulsen

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christine Hui · 1994 to 2026
$57.9M
Development of A Multi-Modality System for Onco-ImagingR33CA120175 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2008 to 2010
$1.5M
Tomographic Molecular Imaging for Breast CancerR01EB008716 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2008 to 2011
$1.3M
Turn the heat on: High resolution fluorescence imaging via temperature modulationR21CA191389 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2015 to 2016
$407k
Fluorescence Tomography in Small Animal Imaging using an Ultra-fast RTE SolverR21EB013387 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GAO, HAO · 2011 to 2012
$345k
Development of A Multi-Modality System for Onco-ImagingR21CA120175 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GULSEN, GULTEKIN · 2007 to 2007
$225k
Photomagnetic Imaging: A Novel Modality for Cancer ImagingF31CA171745 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI LUK, ALEX T · 2013 to 2015
$128k
Temperature Modulated-Fluorescence Tomography: A New Modality for Cancer ImagingF31CA171915 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI KWONG, TIFFANY · 2012 to 2014
$106k
NCI NIH HHS F31 CA171745NCI NIH HHS F31 CA171915NCI NIH HHS HHSN261201300068CNCI NIH HHS P30 CA062203NCI NIH HHS R21 CA120175NCI NIH HHS R21 CA191389NCI NIH HHS R33 CA120175NIBIB NIH HHS R01 EB008716NIBIB NIH HHS R21 EB013387
6 · The paper itself

Abstract

We recently introduced a new high-resolution diffuse optical imaging technique termed photo-magnetic imaging (PMI), which utilizes magnetic resonance thermometry (MRT) to monitor the 3D temperature distribution induced in a medium illuminated with a near-infrared light. The spatiotemporal temperature distribution due to light absorption can be accurately estimated using a combined photon propagation and heat diffusion model. High-resolution optical absorption images are then obtained by iteratively minimizing the error between the measured and modeled temperature distributions. We have previously demonstrated the feasibility of PMI with experimental studies using tissue simulating agarose phantoms. In this Letter, we present the preliminary ex vivo PMI results obtained with a chicken breast sample. Similarly to the results obtained on phantoms, the reconstructed images reveal that PMI can quantitatively resolve an inclusion with a 3 mm diameter embedded deep in a biological tissue sample with only 10% error. These encouraging results demonstrate the high performance of PMI in ex vivo biological tissue and its potential for in vivo imaging.

Indexed as

Image Processing, Computer-AssistedBreastFemaleHumansPhantoms, ImagingPhotonsThermometry

Identifiers

PMID29028040
PMCPMC6855589

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.