ArticleThe ISME journal2018
Microbiome and infectivity studies reveal complex polyspecies tree disease in Acute Oak Decline.
Article in The ISME journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 132 citations in OpenAlex.
- Beyond detection: unveiling microbial dynamics in oak seedlings using fungal isolation and amplicon sequencing.Environmental microbiome · 2026Article
- Characterisation and In Planta Activity of Bacteriophages That Infect the Key Bacterial Species Associated With Acute Oak Decline.Microbial biotechnology · 2026Article
- Microbiome legacy influences necrosis formation in Diplodia sapinea-infected Scots pine shoots.Environmental microbiome · 2026Article
- Multi-omics analysis reveals the pathobiome-host interactions in the bleaching disease of the seaweed Saccharina japonica.Microbiome · 2025Article
- Bacterial Communities Associated With Acute Oak Decline of Sessile Oak (Quercus petraea) in Southern Sweden.Environmental microbiology reports · 2025Article
- Biofilm as a Key Element in the Bacterial Pathogenesis of Forest Trees: A Review of Mechanisms and Ecological Implications.Microorganisms · 2025Review
- Unlocking plant health survey data: An approach to quantify the sensitivity and specificity of visual inspections.PLoS computational biology · 2025Article
- Landscape-scale endophytic community analyses in replicated grapevine stands reveal that dieback disease is unlikely to be caused by specific fungal communities.Applied and environmental microbiology · 2025Article
- Acute Oak Decline-Associated Bacteria: An Emerging Worldwide Threat to Forests.Microorganisms · 2025Review
- Comparative Genomics Analysis of the Fish Pathogen Rahnella aquatilis KCL-5 Reveals Potential Multidrug Resistance and Virulence Properties.Current microbiology · 2025Article
- Evaluating agar-plating and dilution-to-extinction isolation methods for generating oak-associated microbial culture collections.ISME communications · 2025Article
- Metabolic profiling and antibacterial activity of tree wood extracts obtained under variable extraction conditions.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Novel class IIb microcins show activity against Gram-negative ESKAPE and plant pathogens.eLife · 2024Article
- Article
- The Role of Bacteria in Acute Oak Decline in South-West Poland.Microorganisms · 2024Article
- Bacteria Associated with Acute Oak Decline: Where Did They Come From? We Know Where They Go.Microorganisms · 2023Article
- Review
- Population genomic analysis of an emerging pathogen Lonsdalea quercina affecting various species of oaks in western North America.Scientific reports · 2023Article
- The Hydroponic Rockwool Root Microbiome: Under Control or Underutilised?Microorganisms · 2023Review
- Article
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Decline-diseases are complex and becoming increasingly problematic to tree health globally. Acute Oak Decline (AOD) is characterized by necrotic stem lesions and galleries of the bark-boring beetle, Agrilus biguttatus, and represents a serious threat to oak. Although multiple novel bacterial species and Agrilus galleries are associated with AOD lesions, the causative agent(s) are unknown. The AOD pathosystem therefore provides an ideal model for a systems-based research approach to address our hypothesis that AOD lesions are caused by a polymicrobial complex. Here we show that three bacterial species, Brenneria goodwinii, Gibbsiella quercinecans and Rahnella victoriana, are consistently abundant in the lesion microbiome and possess virulence genes used by canonical phytopathogens that are expressed in AOD lesions. Individual and polyspecies inoculations on oak logs and trees demonstrated that B. goodwinii and G. quercinecans cause tissue necrosis and, in combination with A. biguttatus, produce the diagnostic symptoms of AOD. We have proved a polybacterial cause of AOD lesions, providing new insights into polymicrobial interactions and tree disease. This work presents a novel conceptual and methodological template for adapting Koch's postulates to address the role of microbial communities in disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.