ArticleThe ISME journal2018
Microdiversification in genome-streamlined ubiquitous freshwater Actinobacteria.
Article in The ISME journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.
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Who cites it
115 citing papers in PubMed, 274 citations in OpenAlex.
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- Environmental effects on constructed wetland microbial diversity and function in the context of wastewater management.Microbiology spectrum · 2026Article
- The first high-throughput sequencing of bacterioplankton sheds light on bacterial and cyanobacterial diversity in high-altitude Lake Sevan, Armenia.Scientific reports · 2026Article
- Metagenome-based vertical profiling of the Gulf of Mexico highlights its uniqueness and far-reaching effects of freshwater input.Applied and environmental microbiology · 2026Article
- The conserved two-component systems CutRS and CssRS control the protein secretion stress response inmBio · 2026Article
- Upwelling periodically disturbs the ecological assembly of microbial communities in Lake Ontario.ISME communications · 2026Article
- Accumulation of recalcitrant dissolved organic carbon during cyanobacterial blooms in Meiliang Bay, Lake Taihu: insights into the microbial carbon pump.Frontiers in microbiology · 2026Article
- Phylogenomic Tree Reconstruction from Bacterial Genomes.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Ecological success in freshwater lakes: insights from novel cultivated lineages of the abundant Nanopelagicales order.Microbiome · 2025Article
- Spatial Heterogeneity in Methane Biogeochemistry and Prokaryotic Community Structure in Sub-Arctic Waterbodies in Northern Canada.Environmental microbiology · 2025Article
- Core genome expansion inIranian journal of microbiology · 2025Article
- Widely-distributed freshwater microorganisms with streamlined genomes co-occur in cohorts with high abundance.Scientific reports · 2025Article
- Spatio-Temporal Resolution of Microbial Functions and Taxa Associated With Cyanobacterial Harmful Algae Blooms Along a 500-Km Aquatic Continuum in the Lake Erie Watershed.Environmental microbiology · 2025Article
- Host-virome associations in the weathering crust of a rapidly retreating temperate Alpine glacier.Microbial genomics · 2025Article
- Ecophysiology and global dispersal of the freshwater SAR11-IIIb genus Fontibacterium.Nature microbiology · 2025Article
- Bringing the uncultivated microbial majority of freshwater ecosystems into culture.Nature communications · 2025Article
- Winter microbial community structure and methane-cycling potential in constructed agricultural wetlands across regions and microhabitats.FEMS microbiology ecology · 2025Article
- Freshwater Discharge and Salinity Drive Taxonomic and Functional Turnover of Microbial Communities in a Turbid Macrotidal Estuary.Environmental microbiology reports · 2025Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Actinobacteria of the acI lineage are the most abundant microbes in freshwater systems, but there are so far no pure living cultures of these organisms, possibly because of metabolic dependencies on other microbes. This, in turn, has hampered an in-depth assessment of the genomic basis for their success in the environment. Here we present genomes from 16 axenic cultures of acI Actinobacteria. The isolates were not only of minute cell size, but also among the most streamlined free-living microbes, with extremely small genome sizes (1.2-1.4 Mbp) and low genomic GC content. Genome reduction in these bacteria might have led to auxotrophy for various vitamins, amino acids and reduced sulphur sources, thus creating dependencies to co-occurring organisms (the 'Black Queen' hypothesis). Genome analyses, moreover, revealed a surprising degree of inter- and intraspecific diversity in metabolic pathways, especially of carbohydrate transport and metabolism, and mainly encoded in genomic islands. The striking genotype microdiversification of acI Actinobacteria might explain their global success in highly dynamic freshwater environments with complex seasonal patterns of allochthonous and autochthonous carbon sources. We propose a new order within Actinobacteria ('Candidatus Nanopelagicales') with two new genera ('Candidatus Nanopelagicus' and 'Candidatus Planktophila') and nine new species.
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