Evidence map›Paper›PMID 29027919›Full record

ArticleToxins2017

Shiga Toxins Induce Apoptosis and ER Stress in Human Retinal Pigment Epithelial Cells.

Jun-Young Park, Yu-Jin Jeong, Sung-Kyun Park, Sung-Jin Yoon, Song Choi, Dae Gwin Jeong, Su Wol Chung, Byung Joo Lee, Jeong Hun Kim, Vernon L Tesh and 2 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Shiga Toxin Induces ApoptosisJournal of microbiology and biotechnology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. The Deletion ofJournal of bacteriology · 2021
    Article
  8. Molecular Biology ofToxins · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Jun-Young ParkMetabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Daejeon 34141, South Korea. pi1812@kribb.re.kr.
Yu-Jin JeongInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Daejeon 34141, South Korea. lfllying@kribb.re.kr.
Sung-Kyun ParkInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Daejeon 34141, South Korea. skpark@kribb.re.kr.
Sung-Jin YoonMetabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Daejeon 34141, South Korea. sjy04@kribb.re.kr.ORCID 0000-0002-7372-0231
Song ChoiMetabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Daejeon 34141, South Korea. ssong@kribb.re.kr.
Dae Gwin JeongInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Daejeon 34141, South Korea. dgjeong@kribb.re.kr.
Su Wol ChungSchool of Biological Sciences, College of Natural Sciences, University of Ulsan, 93 Daehak-ro, Ulsan 44610, South Korea. swchung@ulsan.ac.kr.
Byung Joo LeeFight Against Angiogenesis-Related Blindness Laboratory, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, South Korea. ozma805@empas.com.
Jeong Hun KimFight Against Angiogenesis-Related Blindness Laboratory, Biomedical Research Institute, Seoul National University Hospital, Seoul 03080, South Korea. steph25@snu.ac.kr.
Vernon L TeshDepartment of Microbial Pathogenesis and Immunology, Texas A&M University Health Science Center, Bryan, TX 77807, USA. tesh@medicine.tamhsc.edu.
Moo-Seung LeeInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Daejeon 34141, South Korea. msl031000@kribb.re.kr.
Young-Jun ParkMetabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Daejeon 34141, South Korea. pyj71@kribb.re.kr.
Korea Research Institute of Bioscience and Biotechnology · KRSeoul National University Hospital · KRKonyang University · KRTexas A&M Health Science Center · USUniversity of Ulsan · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shiga toxins (Stxs) produced by Shiga toxin-producing bacteria

Indexed as

ApoptosisCaspasesCell LineEndoplasmic Reticulum StressEpithelial CellsHumansMembrane Potential, MitochondrialMitogen-Activated Protein KinasesRetinal Pigment EpitheliumShiga Toxin 1Shiga Toxin 2CaspasesMitogen-Activated Protein KinasesShiga Toxin 1Shiga Toxin 2apoptosishemolytic uremic syndromeretinal pigment epithelial cellsShiga toxin-producing Escherichia coliShiga toxinsShiga toxin type 1 and 2signaling pathways

Identifiers

PMID29027919
PMCPMC5666366
OpenAlexW2763554852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.