Evidence map›Paper›PMID 29027884›Full record

ArticleTelemedicine journal and e-health : the official journal of the American Telemedicine Association2018

Accuracy and Reliability of a Handheld, Nonmydriatic Fundus Camera for the Remote Detection of Optic Disc Edema.

Lulu Bursztyn, Maria A Woodward, Wayne T Cornblath, Hilary M Grabe, Jonathan D Trobe, Leslie Niziol, Lindsey B De Lott

Open access · greenAbstract read
In one paragraph

Article in Telemedicine journal and e-health : the official journal of the American Telemedicine Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. The Use Of Fundus Photography In The Emergency Room-A Review.Current neurology and neuroscience reports · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Diagnostic Error in Neuro-ophthalmology: Avenues to Improve.Current neurology and neuroscience reports · 2022
    Review
  10. Article
  11. Article
  12. Telemedicine in ophthalmology in view of the emerging COVID-19 outbreak.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lulu Bursztyn1 Department of Ophthalmology, Western University , London, Ontario, Canada .
Maria A Woodward2 Department of Ophthalmology & Visual Sciences, University of Michigan , Ann Arbor, Michigan.
Wayne T Cornblath2 Department of Ophthalmology & Visual Sciences, University of Michigan , Ann Arbor, Michigan.
Hilary M Grabe3 Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern , Bern, Switzerland .
Jonathan D Trobe2 Department of Ophthalmology & Visual Sciences, University of Michigan , Ann Arbor, Michigan.
Leslie Niziol2 Department of Ophthalmology & Visual Sciences, University of Michigan , Ann Arbor, Michigan.
Lindsey B De Lott2 Department of Ophthalmology & Visual Sciences, University of Michigan , Ann Arbor, Michigan.
University of Bern · CHWestern University · CA

Funding

Telemedicine For Anterior Eye DiseasesK23EY023596 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WOODWARD, MARIA ANNEKE · 2013 to 2017
$1.1M
NEI NIH HHS K23 EY023596
6 · The paper itself

Abstract

backgroundOptic disc edema can be an important indicator of serious neurological disease, but is poorly detected using the direct ophthalmoscope. Portable fundus photography may overcome this difficulty.

introductionThe purpose of this study was to determine the sensitivity and specificity of a handheld, nonmydriatic fundus camera for the detection of optic disc edema. MATERIALS AND

methodsRetrospective review of nonmydriatic optic disc photographs taken with a portable fundus camera (Pictor Plus; Volk Optical, Mentor, OH) from the University of Michigan Neuro-Ophthalmology Clinics. We included 103 consecutive eyes with optic disc edema and 103 consecutive eyes without optic disc edema of 109 patients. Four masked neuro-ophthalmologists graded a single photograph of each optic disc presented in randomized order and documented the presence of optic disc edema. Sensitivity and specificity of graders' photographic interpretation was compared with clinical examinations. Reliability of assessments within and between graders was determined using kappa statistics.

resultsThe sensitivity and specificity for detection of optic disc edema were 71.8-92.2% and 81.6-95.2%, respectively. Photos were found to be ungradable in 0-8.3% of cases. The intergrader reliabilities ranged from 0.60 [95% confidence interval (CI): 0.52-0.67] to 0.72 (95% CI: 0.66-0.77). Intragrader reliability ranged from 0.76 (95% CI: 0.63-0.92) to 0.82 (95% CI: 0.69-0.95). DISCUSSION: Photographs taken with portable, nonmydriatic technology met threshold sensitivity and specificity for remote screening for optic disc edema when performed by most, but not all graders. Reliability between graders was moderate-strong and strong within individual providers.

conclusionsPortable photography holds promise for use in remote screening of optic disc edema.

Indexed as

Diagnostic Techniques, OphthalmologicalEdemaFemaleFundus OculiHumansMaleObserver VariationOptic Nerve DiseasesPhotographyPoint-of-Care SystemsReproducibility of ResultsRetrospective StudiesSensitivity and Specificityemergency medicineophthalmologytelehealthtelemedicineteletrauma

Identifiers

PMID29027884
PMCPMC5953213
OpenAlexW2761227467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.