ArticleJournal of neurosurgery2018
Role of the temporal pole in temporal lobe epilepsy seizure networks: an intracranial electrode investigation.
Article in Journal of neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Semiology of seizures with temporo-polar or "medio-lateral" temporal origin: A systematic review.Epileptic disorders : international epilepsy journal with videotape · 2025Pooled it
- An examination of seizure-free outcome and visual field deficits: Anterior temporal lobectomy versus selective amygdalohippocampectomy for temporal lobe epilepsy-a systematic review and meta-analysis for comprehensive understanding.Acta neurochirurgica · 2024Pooled it
- Divergent Propagation Networks Define Two Pathophysiologically Distinct Electroclinical Phenotypes in Mesial Temporal Lobe Epilepsy.Journal of clinical neurology (Seoul, Korea) · 2026Article
- Temporopolar epilepsy stereoEEG: implant technique and outcomes.Epilepsy & behavior reports · 2025Article
- Altered Directed-Connectivity Network in Temporal Lobe Epilepsy: A MEG Study.Sensors (Basel, Switzerland) · 2025Article
- Temporopolar blurring signifies abnormalities of white matter in mesial temporal lobe epilepsy.Annals of clinical and translational neurology · 2024Article
- The anterior sylvian point as a reliable landmark for the anterior temporal lobectomy in mesial temporal lobe epilepsy: technical note, case series, and cadaveric dissection.Frontiers in medicine · 2024Article
- Normative brain mapping using scalp EEG and potential clinical application.Scientific reports · 2023Article
- Article
- Altered metabolic-functional coupling in the epileptogenic network could predict surgical outcomes of mesial temporal lobe epilepsy.Frontiers in neuroscience · 2023Article
- Temporal lobe epilepsy lateralisation and surgical outcome prediction using diffusion imaging.Journal of neurology, neurosurgery, and psychiatry · 2022Article
- Long-Term Outcome of Temporal Lobe Epilepsy Surgery in 621 Patients With Hippocampal Sclerosis: Clinical and Surgical Prognostic Factors.Frontiers in neurology · 2022Article
- Correlation Between Ictal Signs and Anatomical Subgroups in Temporal Lobe Seizures: A Stereoelectroencephalography Study.Frontiers in neurology · 2022Article
- Altered voxel-mirrored homotopic connectivity in right temporal lobe epilepsy as measured using resting-state fMRI and support vector machine analyses.Frontiers in psychiatry · 2022Article
- Impaired Topological Properties of Gray Matter Structural Covariance Network in Epilepsy Children With Generalized Tonic-Clonic Seizures: A Graph Theoretical Analysis.Frontiers in neurology · 2020Article
- NR4A1 Methylation Associated Multimodal Neuroimaging Patterns Impaired in Temporal Lobe Epilepsy.Frontiers in neuroscience · 2020Article
- Amygdala enlargement in mesial temporal lobe epilepsy: an alternative imaging presentation of limbic epilepsy.Neuroradiology · 2019Article
- Stereoelectroencephalography Versus Subdural Electrodes for Localization of the Epileptogenic Zone: What Is the Evidence?Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019Review
- Cortical Surface Area Rather Than Cortical Thickness Potentially Differentiates Radiation Encephalopathy at Early Stage in Patients With Nasopharyngeal Carcinoma.Frontiers in neuroscience · 2018Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
OBJECTIVE A convergence of clinical research suggests that the temporal pole (TP) plays an important and potentially underappreciated role in the genesis and propagation of seizures in temporal lobe epilepsy (TLE). Understanding its role is becoming increasingly important because selective resections for medically intractable TLE spare temporopolar cortex (TPC). The purpose of this study was to characterize the role of the TPC in TLE after using dense electrocorticography (ECoG) recordings in patients undergoing invasive monitoring for medically intractable TLE. METHODS Chronic ECoG recordings were obtained in 10 consecutive patients by using an array customized to provide dense coverage of the TP as part of invasive monitoring to localize the epileptogenic zone. All patients would eventually undergo cortico-amygdalohippocampectomy. A retrospective review of the patient clinical records including ECoG recordings, neuroimaging studies, neuropathology reports, and clinical outcomes was performed. RESULTS In 7 patients (70%), the TP was involved at seizure onset; in 7 patients (70%), there were interictal discharges from the TP; and in 1 case, there was early spread to the TP. Seizure onset in the TP did not necessarily correlate with preoperative neuroimaging abnormalities of the TP. CONCLUSIONS These data demonstrate that TPC commonly plays a crucial role in temporal lobe seizure networks. Seizure onset from the TP would not have been predicted based on available neuroimaging data or interictal discharges. These findings illustrate the importance of thoroughly considering the role of the TP prior to resective surgery for TLE, particularly when selective mesial resection is being considered.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.