Evidence map›Paper›PMID 29027615›Full record

ArticlePathology oncology research : POR2019

Assessment of the Role of Everolimus Therapy in Patients with Renal Cell Carcinoma Based on Daily Routine and Recent Research Results.

Anikó Maráz, András Csejtei, Judit Kocsis, Miklós Szűcs, Zsuzsanna Kahán, György Bodoky, Magdolna Dank, László Mangel, János Révész, Zoltán Varga and 1 more

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In one paragraph

Article in Pathology oncology research : POR, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Anikó MarázDepartment of Oncotherapy, University of Szeged, Korányi fasor 12, Szeged, 6720, Hungary. dr.aniko.maraz@gmail.com.ORCID http://orcid.org/0000-0002-2018-8413
András CsejteiMarkusovszky Teaching Hospital, Markusovszky str. 5, Szombathely, Hungary.
Judit KocsisInstitute of Oncology, University of Debrecen, Nagyerdei krt. 98., Debrecen, Hungary.
Miklós SzűcsFaculty of Medicine, Department of Urology and Urooncological Centre, Semmelweis University, Üllői str. 78/b, Budapest, Hungary.
Zsuzsanna KahánDepartment of Oncotherapy, University of Szeged, Korányi fasor 12, Szeged, 6720, Hungary.
György BodokyDepartment of Oncology, Integrated St. Istvan and St. Laszlo Hospital, Albert Flórián str. 5-7, Budapest, Hungary.
Magdolna DankFaculty of Medicine, 1st Department of Internal Medicine, Division of Oncology, Semmelweis University, Tömő str.25-29, Budapest, Hungary.
László MangelInstitute of Oncotherapy, University of Pécs, Édesanyák 17., Pécs, Hungary.
János RévészInstitute of Radiotherapy and Clinical Oncology, Borsod County Hospital and University Academic Hospital, Szentpéteri Kapu 72-76, Miskolc, Hungary.
Zoltán VargaDepartment of Oncotherapy, University of Szeged, Korányi fasor 12, Szeged, 6720, Hungary.
Lajos GécziNational Institute of Oncology, Chemotherapy C and Clinical Pharmacology, Ráth György str. 7-9, Budapest, Hungary.
University of Szeged · HUSemmelweis University · HUMarkusovszky Egyetemi Oktatókórház · HUNational Institute of Oncology · HUUnified Szent István and Szent László Hospital · HUUniversity of Debrecen · HUUniversity of Pecs · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Everolimus is indicated for adults with metastatic renal cell carcinoma (mRCC) after failure of vascular endothelial growth factor receptor-tyrosine kinase inhibitors (TKI). Currently, the therapeutic applicability of EVE has been changing. Multicenter evaluation of efficacy and safety of everolimus in daily routine and definition of patient characteristics with favorable outcome. Data of 165 patients from 9 oncology institutes in Hungary were analyzed retrospectively. Everolimus therapy was used after one TKI in 10 mg starting dose. Physical and laboratory examinations and imaging tests were performed monthly and every 3 months, respectively. Median progression-free survival (PFS) was 5.4 months. Median overall survival (OS) was 16.2 months. PFS and OS results were more favorable in patients with ECOG 0-1 (p

Indexed as

AdultAgedAntineoplastic AgentsCarcinoma, Renal CellEverolimusFemaleFollow-Up StudiesHumansKidney NeoplasmsMaleMiddle AgedRetrospective StudiesSurvival RateTreatment OutcomeAntineoplastic AgentsEverolimusAnemiaECOGEverolimusMetastatic kidney cancermTOR inhibitorRCC

Identifiers

PMID29027615
OpenAlexW2760990254

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.