ArticleInternational ophthalmology2018
Review of people with retinal vasculitis and positive QuantiFERON
Article in International ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- A systemic review of the utility of antituberculosis therapy for presumed tuberculous uveitis.BMC infectious diseases · 2025Pooled it
- Systemic vasculitis with latent tuberculosis infection and associated factors: a cross-sectional multicenter study.Clinical rheumatology · 2025Article
- Clinical manifestation and long-term follow-up of presumed ocular tuberculosis in China.Journal of clinical tuberculosis and other mycobacterial diseases · 2024Article
- Differences betweenJournal of clinical medicine · 2021Review
- [Treatment of ocular tuberculosis-an update].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2020Review
- Clinical and Epidemiological Study on Tubercular Uveitis in a Tertiary Eye Care Centre in Italy.Journal of ophthalmology · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the frequency of a positive QuantiFERON
methodsConsecutive patients with retinal vasculitis and a positive quantiferon were retrospectively analyzed. Demographics, clinical data, laboratory, imaging findings, and therapy were evaluated.
resultsAmong 49 patients with retinal vasculitis, 12 (24%) had a positive quantiferon. Median age was 37 years, there were five female patients. Five individuals (42%) had previously lived in a country endemic for TB. Retinal vasculitis was occlusive in six patients (50%). On chest imaging, pulmonary tuberculosis was suspected in one patient (8.3%). Treatment modalities included full antitubercular treatment (n = 1), isoniazid prophylaxis (n = 6), systemic corticosteroids (n = 8), and laser treatment (n = 5). After a median follow-up of 27.5 months, inflammation was inactive (n = 6) or recurrently present (n = 6). No patient lost ≥ 2 lines of best-corrected visual acuity during follow-up.
conclusionsThe quantiferon test is recommended in the evaluation of people with retinal vasculitis. Interpretation of a positive result can be challenging in a country nonendemic for TB. The majority of patients with quantiferon-positive retinal vasculitis were found to have latent TB.
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