Evidence map›Paper›PMID 29027568›Full record

ReviewDer Internist2017

[Diagnostics and treatment of acromegaly : Necessity for targeted monitoring of comorbidities].

S Petersenn, M Christ-Crain, M Droste, R Finke, J Flitsch, I Kreitschmann-Andermahr, A Luger, J Schopohl, G Stalla

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Internist, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 3 countries.

S PetersennENDOC Praxis für Endokrinologie, Andrologie und medikamentöse Tumortherapie, Erik-Blumenfeld-Platz 27A, 22587, Hamburg, Deutschland. stephan.petersenn@endoc-med.de.
M Christ-CrainEndokrinologie, Diabetologie & Metabolismus, Universitätsspital Basel, Basel, Schweiz.
M DrosteEndokrinologie, Diabetologie, Hormonanalytik, Medicover MVZ, Oldenburg, Deutschland.
R FinkeInnere Medizin, Endokrinologie/Diabetologie & Allgemeinmedizin, Praxisgemeinschaft an der Kaisereiche, Berlin, Deutschland.
J FlitschKlinik und Poliklinik für Neurochirurgie, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.
I Kreitschmann-AndermahrNeurochirurgische Klinik, Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Deutschland.
A LugerKlinische Abteilung für Endokrinologie & Stoffwechsel, Universitätsklinik für Innere Medizin III, Medizinische Universität Wien, Wien, Österreich.
J SchopohlMedizinische Klinik und Poliklinik IV, Klinikum der Universität München, München, Deutschland.
G StallaInnere Medizin, Endokrinologie und Klinische Chemie, Max-Planck-Institut für Psychiatrie, München, Deutschland.
Endokrinologikum · DEEssen University Hospital · DEKlinik und Poliklinik für Neurologie · DELMU Klinikum · DEMax Planck Institute of Psychiatry · DEMedical University of Vienna · ATMedicover · DEUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acromegaly is a rare and severe condition, presenting with typical signs and symptoms. The diagnosis is often initially made years after the first manifestations of the disease. In more than 99% of patients the disease is caused by a benign pituitary tumor that secretes growth hormone (GH). The diagnosis is based on the presence of increased insulin-like growth factor 1 (IGF-1) levels and a lack of GH suppression in the oral glucose tolerance test. The standard imaging procedure for tumor detection is magnetic resonance imaging in the region of the sella turcica. Treatment includes surgical, drug and radiation therapy. Important factors are an intensive aftercare of the patient, controls for detection of tumor recurrence and pituitary insufficiency as well as assessment of various organ functions and risk constellations. Patient care should involve close cooperation between endocrinologists, neurosurgeons and general practitioners as well as other specialist disciplines.

Indexed as

AcromegalyAdenomaComorbidityDiagnosis, DifferentialGrowth Hormone-Secreting Pituitary AdenomaHumansInsulin-Like Growth Factor IInterdisciplinary CommunicationIntersectoral CollaborationRare DiseasesIGF1 protein, humanInsulin-Like Growth Factor ICardiovascular diseasesEndocrine system diseasesInsulin-like growth factor IPituitary adenomaSleep apnea syndromes

Identifiers

PMID29027568
OpenAlexW2768641872

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.