Evidence map›Paper›PMID 29027544›Full record

ReviewNature reviews. Neurology2017

Long-term effects of exercise and physical therapy in people with Parkinson disease.

Margaret K Mak, Irene S Wong-Yu, Xia Shen, Chloe L Chung

5 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 272 papers, 27 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
272citing papers in PubMed, 27 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03563807 nacompletednot on this mapstarted 2018, after this paper: background citation

Feasibility and Tolerability of Group Golf Instruction Versus Tai Chi for Patients With Moderate to Advanced Parkinson's Disease

TypeinterventionalSponsorMassachusetts General HospitalRan2018 to 2020Enrolled35ConditionsParkinson Disease, Movement Disorders, Neuro-Degenerative DiseaseArmsGolf Instruction, Tai Chi Class
NCT03974529 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Intensive Running Exercise Improves Parkinson's Motor and Non-motor Symptoms

TypeinterventionalSponsorChinese University of Hong KongRan2018 to 2020Enrolled30ConditionsParkinson DiseaseArmsIntensive running, Physiotherapy
NCT04048291 nacompletednot on this mapstarted 2018, after this paper: background citation

Efficacy of Brisk Walking on Improving Balance and Gait Performance, and Functional Mobility in Parkinson's Disease - a Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2018 to 2020Enrolled80ConditionsParkinson DiseaseArmsBrisk walking and balance training, Upper limb exercise
NCT04665869 nacompletednot on this mapstarted 2020, after this paper: background citation

Long-term Effects of Combined Balance and Brisk Walking on Alleviating Motor and Non-motor Symptoms in Parkinson's Disease: a Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2020 to 2022Enrolled100ConditionsParkinson DiseaseArmsCombined balance and brisk walking training, Flexibility and strengthening exercise
NCT05502718 narecruitingnot on this mapstarted 2022, after this paper: background citation

Evaluation of the Effect of Personalized Exercise Program on Clinical Findings and Quality of Life of Patients With Cervical Dystonia Who Received Botulinum Toxin Type A Injection

TypeinterventionalSponsorProf. Dr. Şehim KutlayRan2022 to 2025Enrolled34ConditionsDystonia, CervicalArmsStretching and Strengthening Exercises, Breathing and Rhythmic Coordination Exercises
3 · Its place in the literature

Who cites it

272 citing papers in PubMed, 27 syntheses or guidelines pooled it.

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212 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Margaret K MakDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, 11 Yuk Choi Road, Hung Hom, Kowloon, Hong Kong.
Irene S Wong-YuDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, 11 Yuk Choi Road, Hung Hom, Kowloon, Hong Kong.
Xia ShenDepartment of Sports Sciences and Physical Education, The Chinese University of Hong Kong, Kwok Sports Building, University Avenue, Shatin, New Territories, Hong Kong.
Chloe L ChungDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, 11 Yuk Choi Road, Hung Hom, Kowloon, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson disease (PD) is a progressive, neurodegenerative movement disorder with symptoms reflecting various impairments and functional limitations, such as postural instability, gait disturbance, immobility and falls. In addition to pharmacological and surgical management of PD, exercise and physical therapy interventions are also being actively researched. This Review provides an overview of the effects of PD on physical activity - including muscle weakness, reduced aerobic capacity, gait impairment, balance disorders and falls. Previously published reviews have discussed only the short-term benefits of exercises and physical therapy for people with PD. However, owing to the progressive nature of PD, the present Review focuses on the long-term effects of such interventions. We also discuss exercise-induced neuroplasticity, present data on the possible risks and adverse effects of exercise training, make recommendations for clinical practice, and describe new treatment approaches. Evidence suggests that a minimum of 4 weeks of gait training or 8 weeks of balance training can have positive effects that persist for 3-12 months after treatment completion. Sustained strength training, aerobic training, tai chi or dance therapy lasting at least 12 weeks can produce long-term beneficial effects. Further studies are needed to verify disease-modifying effects of these interventions.

Indexed as

Exercise TherapyPhysical Therapy ModalitiesAccidental FallsDance TherapyGait Disorders, NeurologicHealth BehaviorHumansNeuronal PlasticityParkinson DiseasePatient CompliancePhysical FitnessPostural BalanceSensation DisordersTai Ji

Identifiers

PMID29027544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.