SynthesisJournal of gynecologic oncology2017
Transvaginal ultrasound versus magnetic resonance imaging for preoperative assessment of myometrial infiltration in patients with endometrial cancer: a systematic review and meta-analysis.
Synthesis in Journal of gynecologic oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Diagnostic value of contrast-enhanced ultrasound for the depth of myometrial infiltration in early endometrial cancer: a meta-analysis.Frontiers in oncology · 2025Pooled it
- Circulating microRNAs as Potential Biomarkers for the Diagnosis of Endometrial Cancer: a Meta-Analysis.Reproductive sciences (Thousand Oaks, Calif.) · 2023Pooled it
- Three-dimensional transvaginal ultrasound vs magnetic resonance imaging for preoperative staging of deep myometrial and cervical invasion in patients with endometrial cancer: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022Pooled it
- ESGO/ESTRO/ESP Guidelines for the management of patients with endometrial carcinoma.Virchows Archiv : an international journal of pathology · 2021Guideline
- Endometrial thickness and cancer risk in asymptomatic postmenopausal women: Defining evidence-based cut-offs by systematic review and diagnostic meta-analysis.Experimental and therapeutic medicine · 2026Article
- Fertility-sparing treatments for patients with endometrial cancer: A comprehensive review.Clinical and experimental reproductive medicine · 2026Article
- Node-RADS for preoperative locoregional nodal staging of endometrial cancer: reproducibility and accuracy assessment using CT and MRI.European radiology · 2026Article
- Impact of Body Mass Index on Robotic Surgery Outcomes in Early-Stage Endometrial Cancer: A Retrospective Cohort Study.Cancers · 2025Article
- A Radiomic-based model to predict the depth of myometrial invasion in endometrial cancer on ultrasound images.Scientific reports · 2025Article
- Improving the diagnosis of endometrial cancer in postmenopausal women in primary care settings using an artificial intelligence-based ultrasound detecting model.Frontiers in oncology · 2025Article
- Review
- Ultrasound in endometrial cancer: evaluating the impact of pre-surgical staging.Oncology reviews · 2025Review
- Review
- Multiparametric magnetic resonance imaging-based assessment of the effect of adenomyosis on determining the depth of myometrial invasion in endometrial cancer.Quantitative imaging in medicine and surgery · 2024Article
- Performance of MRI for Detection of ≥pT1b Disease in Local Staging of Endometrial Cancer.Cancers · 2024Article
- Staging by imaging in gynecologic cancer and the role of ultrasound: an update of European joint consensus statements.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024Review
- Review
- Can the microcystic, elongated and fragmented pattern of invasion influence the evaluation of the depth of myometrial invasion in low-grade endometrioid endometrial cancer using imaging techniques?Ultrasound (Leeds, England) · 2023Article
- Diagnostic Performance of Preoperative Imaging in Endometrial Cancer.Current oncology (Toronto, Ont.) · 2023Article
- Conservative treatment of endometrial cancer in women of reproductive age (Review).Molecular and clinical oncology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the diagnostic accuracy of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for detecting myometrial infiltration (MI) in endometrial carcinoma.
methodsAn extensive search of papers comparing TVS and MRI in assessing MI in endometrial cancer was performed in MEDLINE (PubMed), Web of Science, and Cochrane Database from January 1989 to January 2017. Quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool.
resultsOur extended search identified 747 citations but after exclusions we finally included in the meta-analysis 8 articles. The risk of bias for most studies was low for most 4 domains assessed in QUADAS-2. Overall, pooled estimated sensitivity and specificity for diagnosing deep MI were 75% (95% confidence interval [CI]=67%-82%) and 82% (95% CI=75%-93%) for TVS, and 83% (95% CI=76%-89%) and 82% (95% CI=72%-89%) for MRI, respectively. No statistical differences were found when comparing both methods (p=0.314). Heterogeneity was low for sensitivity and high for specificity for TVS and MRI.
conclusionMRI showed a better sensitivity than TVS for detecting deep MI in women with endometrial cancer. However, the difference observed was not statistically significant.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.