Evidence map›Paper›PMID 29026973›Full record

ReviewPlant cell reports2018

Active DNA demethylation: mechanism and role in plant development.

Yan Li, Suresh Kumar, Weiqiang Qian

Open access · hybridAbstract readReview
In one paragraph

Review in Plant cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 109 citations in OpenAlex.

  1. Review
  2. Article
  3. Epigenetics in Space: The Dynamic Cellular Response.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Insights into the Epigenetic Basis of Plant Salt Tolerance.International journal of molecular sciences · 2024
    Review
  10. Article
  11. Transcriptional Silencing of 35S rDNA inInternational journal of molecular sciences · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Yan LiState Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Peking University, Beijing, 100871, China.
Suresh KumarDivision of Biochemistry, ICAR-Indian Agricultural Research Institute, New Delhi, 110012, India.
Weiqiang QianState Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, School of Life Sciences, Peking University, Beijing, 100871, China. wqqian@pku.edu.cn.ORCID http://orcid.org/0000-0002-3135-6689
Peking University · CNIndian Agricultural Research Institute · IN

Funding

National Natural Science Foundation of China 31522005
6 · The paper itself

Abstract

Active DNA demethylation (enzymatic removal of methylated cytosine) regulates many plant developmental processes. In Arabidopsis, active DNA demethylation entails the base excision repair pathway initiated by the Repressor of silencing 1/Demeter family of bifunctional DNA glycosylases. In this review, we first present an introduction to the recent advances in our understanding about the mechanisms of active DNA demethylation. We then focus on the role of active DNA demethylation in diverse developmental processes in various plant species, including the regulation of seed development, pollen tube formation, stomatal development, fruit ripening, and nodule development. Finally, we discuss future directions of research in the area of active DNA demethylation.

Indexed as

DemethylationDNA GlycosylasesDNA, PlantFruitGene Expression Regulation, PlantGenomic ImprintingPlant DevelopmentPollen TubeSeedsSeed Storage ProteinsDNA GlycosylasesDNA, PlantSeed Storage ProteinsActive DNA demethylationDemeterDNA methylationPlant developmentROS1

Identifiers

PMID29026973
PMCPMC5758694
OpenAlexW2760920524

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.